Mechanisms and biomarkers of successful allergen-specific immunotherapy
JF López, MB Imam, P Satitsuksanoa, S Lems… - Asia Pacific …, 2022 - journals.lww.com
Allergen-specific immunotherapy (AIT) is considered the only curative treatment for allergic
diseases mediated by immunoglobulin E (IgE). Currently, the route of administration …
diseases mediated by immunoglobulin E (IgE). Currently, the route of administration …
C-type lectin receptor mediated modulation of T2 immune responses to allergens
A Angelina, L Martín-Cruz… - Current Allergy and …, 2023 - Springer
Abstract Purpose of Review Allergic diseases represent a major health problem of
increasing prevalence worldwide. In allergy, dendritic cells (DCs) contribute to both the …
increasing prevalence worldwide. In allergy, dendritic cells (DCs) contribute to both the …
Enhancement of β-Glucan Biological Activity Using a Modified Acid-Base Extraction Method from Saccharomyces cerevisiae
Beta glucan (β-glucan) has promising bioactive properties. Consequently, the use of β-
glucan as a food additive is favored with the dual-purpose potential of increasing the fiber …
glucan as a food additive is favored with the dual-purpose potential of increasing the fiber …
β-glucan nanoparticles alleviate acute asthma by suppressing ferroptosis and DNA damage in mice
Asthma is a severe respiratory disease marked by airway inflammation, remodeling, and
oxidative stress. β-Glucan (BG), a polysaccharide constituent of fungal cellular structures …
oxidative stress. β-Glucan (BG), a polysaccharide constituent of fungal cellular structures …
Treating allergies via skin–recent advances in cutaneous allergen immunotherapy
Subcutaneous allergen immunotherapy has been practiced clinically for decades to treat
airborne allergies. Recently, the cutaneous route, which exploits the immunocompetence of …
airborne allergies. Recently, the cutaneous route, which exploits the immunocompetence of …
Recent advances in epicutaneous immunotherapy and potential applications in food allergy
PL Hervé, V Dioszeghy, K Matthews, KJ Bee… - Frontiers in …, 2023 - frontiersin.org
Given the potent immunological properties of the skin, epicutaneous immunotherapy (EPIT)
emerges as a promising treatment approach for inducing immune tolerance, particularly for …
emerges as a promising treatment approach for inducing immune tolerance, particularly for …
Carbohydrates in allergy: from disease to novel immunotherapies
BCK Doungstop, SJ Van Vliet, R Van Ree… - Trends in …, 2021 - cell.com
Respiratory allergic disorders are a global public health problem that are responsible for
substantial morbidity and healthcare expenditure. Despite the availability of allergen …
substantial morbidity and healthcare expenditure. Despite the availability of allergen …
The role of regulatory T cells in epicutaneous immunotherapy for food allergy
G Liu, M Liu, J Wang, Y Mou, H Che - Frontiers in Immunology, 2021 - frontiersin.org
In recent decades, a rapid increase in the prevalence of food allergies has led to extensive
research on novel treatment strategies and their mechanisms. Mouse models have provided …
research on novel treatment strategies and their mechanisms. Mouse models have provided …
An epicutaneous therapeutic pollen-allergen extract delivery system in an allergic rhinitis mouse model: based on allergen loading on DC-specific aptamers …
S Pordel, N Haghnavaz, MA Rezaee, SS Shobeiri… - Immunologic …, 2024 - Springer
Abstract Background Gold nanoparticles (GNPs) have previously been suggested as
appropriate carriers for allergen-specific immunotherapy (AIT). In this study, we assessed …
appropriate carriers for allergen-specific immunotherapy (AIT). In this study, we assessed …
A Novel C-type lectin receptor-targeted α-synuclein-based parkinson vaccine induces potent immune responses and therapeutic efficacy in mice
S Schmidhuber, S Scheiblhofer, R Weiss, M Cserepes… - Vaccines, 2022 - mdpi.com
The progressive accumulation of misfolded α-synuclein (α-syn) in the brain is widely
considered to be causal for the debilitating clinical manifestations of synucleinopathies …
considered to be causal for the debilitating clinical manifestations of synucleinopathies …