Natural killer cells: from innate to adaptive features

AM Mujal, RB Delconte, JC Sun - Annual review of immunology, 2021 - annualreviews.org
Natural killer (NK) cells are innate lymphocytes that provide critical host defense against
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …

Controlling natural killer cell responses: integration of signals for activation and inhibition

EO Long, H Sik Kim, D Liu, ME Peterson… - Annual review of …, 2013 - annualreviews.org
Understanding how signals are integrated to control natural killer (NK) cell responsiveness
in the absence of antigen-specific receptors has been a challenge, but recent work has …

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells

Q Hammer, T Rückert, EM Borst, J Dunst… - Nature …, 2018 - nature.com
Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …

Natural killer cell specificity for viral infections

Q Hammer, T Rückert, C Romagnani - Nature immunology, 2018 - nature.com
Natural killer (NK) cells are lymphocytes that contribute to the early immune responses to
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …

Control of human viral infections by natural killer cells

S Jost, M Altfeld - Annual review of immunology, 2013 - annualreviews.org
Natural killer (NK) cells are effector cells of the innate immune system and are important in
the control of viral infections. Their relevance is reflected by the multiple mechanisms …

[HTML][HTML] Virus inhibition of RIP3-dependent necrosis

JW Upton, WJ Kaiser, ES Mocarski - Cell host & microbe, 2010 - cell.com
Viral infection activates cytokine expression and triggers cell death, the modulation of which
is important for successful pathogenesis. Necroptosis is a form of programmed necrosis …

Effect of NKG2D ligand expression on host immune responses

M Champsaur, LL Lanier - Immunological reviews, 2010 - Wiley Online Library
Natural killer group 2, member D (NKG2D) is an activating receptor present on the surface of
natural killer (NK) cells, some NKT cells, CD8+ cytotoxic T cells, γδ T cells, and under certain …

Modulation of innate and adaptive immunity by cytomegaloviruses

R Berry, GM Watson, S Jonjic… - Nature reviews …, 2020 - nature.com
The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …

'Unlicensed'natural killer cells dominate the response to cytomegalovirus infection

MT Orr, WJ Murphy, LL Lanier - Nature immunology, 2010 - nature.com
Natural killer (NK) cells expressing inhibitory receptors that bind to self major
histocompatibility complex (MHC) class I are'licensed', or rendered functionally more …

DCs and NK cells: critical effectors in the immune response to HIV-1

M Altfeld, L Fadda, D Frleta, N Bhardwaj - Nature Reviews Immunology, 2011 - nature.com
Dendritic cells (DCs) and natural killer (NK) cells have central roles in antiviral immunity by
shaping the quality of the adaptive immune response to viruses and by mediating direct …