[HTML][HTML] ATP and adenosine—Two players in the control of seizures and epilepsy development
Despite continuous advances in understanding the underlying pathogenesis of
hyperexcitable networks and lowered seizure thresholds, the treatment of epilepsy remains …
hyperexcitable networks and lowered seizure thresholds, the treatment of epilepsy remains …
ATPergic signalling during seizures and epilepsy
Much progress has been made over the last few decades in the identification of new anti-
epileptic drugs (AEDs). However, 30% of epilepsy patients suffer poor seizure control. This …
epileptic drugs (AEDs). However, 30% of epilepsy patients suffer poor seizure control. This …
Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug‐refractory epilepsy
M Alves, R Gomez‐Villafuertes, N Delanty… - …, 2017 - Wiley Online Library
Objective ATP is released into the extracellular space during pathologic processes including
increased neuronal firing. Once released, ATP acts on P2 receptors including ionotropic …
increased neuronal firing. Once released, ATP acts on P2 receptors including ionotropic …
The metabotropic purinergic P2Y receptor family as novel drug target in epilepsy
Epilepsy encompasses a heterogeneous group of neurological syndromes which are
characterized by recurrent seizures affecting over 60 million people worldwide. Current anti …
characterized by recurrent seizures affecting over 60 million people worldwide. Current anti …
Lipopolysaccharide induced increase in seizure activity in two animal models of absence epilepsy WAG/Rij and GAERS rats and Long Evans rats
We showed previously that the number and time of spike–wave discharges (SWDs) were
increased after intraperitoneal (ip) injection of lipopolysaccharide (LPS), an effect, which …
increased after intraperitoneal (ip) injection of lipopolysaccharide (LPS), an effect, which …
From physiology to pathology of cortico-thalamo-cortical oscillations: astroglia as a target for further research
D Gobbo, A Scheller, F Kirchhoff - Frontiers in Neurology, 2021 - frontiersin.org
The electrographic hallmark of childhood absence epilepsy (CAE) and other idiopathic
forms of epilepsy are 2.5–4 Hz spike and wave discharges (SWDs) originating from …
forms of epilepsy are 2.5–4 Hz spike and wave discharges (SWDs) originating from …
Absence epileptic activity changing effects of non-adenosine nucleoside inosine, guanosine and uridine in Wistar Albino Glaxo Rijswijk rats
Adenosine (Ado) and non-adenosine (non-Ado) nucleosides such as inosine (Ino),
guanosine (Guo) and uridine (Urd) may have regionally different roles in the regulation of …
guanosine (Guo) and uridine (Urd) may have regionally different roles in the regulation of …
Adenosine receptors modulate the exogenous ketogenic supplement-evoked alleviating effect on lipopolysaccharide-generated increase in absence epileptic activity …
B Brunner, C Ari, DP D'Agostino, Z Kovács - Nutrients, 2021 - mdpi.com
It has been previously demonstrated that KEKS food containing exogenous ketogenic
supplement ketone salt (KS) and ketone ester (KE) decreased the lipopolysaccharide (LPS) …
supplement ketone salt (KS) and ketone ester (KE) decreased the lipopolysaccharide (LPS) …
Non-adenosine nucleoside inosine, guanosine and uridine as promising antiepileptic drugs: a summary of current literature
Z Kovács, K A. Kekesi, G Juhász, J Barna… - Mini reviews in …, 2014 - benthamdirect.com
Adenosine (Ado) and some non-adenosine (non-Ado) nucleosides including inosine (Ino),
guanosine (Guo) and uridine (Urd) are modulatory molecules in the central nervous system …
guanosine (Guo) and uridine (Urd) are modulatory molecules in the central nervous system …
Enhancement of ketone supplements-evoked effect on absence epileptic activity by co-administration of uridine in Wistar albino Glaxo Rijswijk rats
B Brunner, E Rauch, C Ari, DP D'Agostino, Z Kovács - Nutrients, 2021 - mdpi.com
Both uridine and exogenous ketone supplements decreased the number of spike-wave
discharges (SWDs) in a rat model of human absence epilepsy Wistar Albino Glaxo/Rijswijk …
discharges (SWDs) in a rat model of human absence epilepsy Wistar Albino Glaxo/Rijswijk …