Outcomes following peripheral nerve injury remain frustratingly poor. The reasons for this
are multifactorial, although maintaining a growth permissive environment in the distal nerve …

Multiple sclerosis (MS) is a chronic inflammatory disease, which leads to focal demyelination
in the brain and spinal cord. Studies showed that iron released during the course of myelin …

Nerve injury is a large problem that produces much pain in patients. Injury to the nervous
system causes serious consequences and affects a person's quality of life. The development …

Retinal ganglion cells (RGCs) degenerate in diseases like glaucoma and are not replaced
in adult mammals. Here we investigate whether transplanted RGCs can integrate into the …

White matter disorders of the central nervous system (CNS), such as multiple sclerosis (MS),
lead to failure of nerve conduction and long-lasting neurological disabilities affecting a …

Background: Inherited optic neuropathies (IONs) cause progressive irreversible visual loss
in children and young adults. There are limited disease-modifying treatments, and most …

Background Inhibitory factors have been implicated in the failure of remyelination in
demyelinating diseases. Myelin associated inhibitors act through a common receptor called …

Diabetic retinopathy (DR) is a leading cause of blindness in all working age groups which
contribute to patient's quality of life. Considering the anatomy and physiology of barriers in …

Sight is a major sense for human and visual impairment profoundly affects quality of life,
especially retinal degenerative diseases which are the leading cause of irreversible …

Methods and Results ADSCs were extracted from adipose tissues from patient.
Immunophenotyping was determined by flow cytometry. Overexpressed EGF or siEGF was …