Mimicking the physical cues of the ECM in angiogenic biomaterials
A functional microvascular system is imperative to build and maintain healthy tissue.
Impaired microvasculature results in ischemia, thereby limiting the tissue's intrinsic …
Impaired microvasculature results in ischemia, thereby limiting the tissue's intrinsic …
[HTML][HTML] Potentials of endothelial colony-forming cells: applications in hemostasis and thrombosis disorders, from unveiling disease pathophysiology to cell therapy
N Schwarz, H Yadegari - Hämostaseologie, 2023 - thieme-connect.com
Endothelial colony-forming cells (ECFCs) are endothelial progenitor cells circulating in a
limited number in peripheral blood. They can give rise to mature endothelial cells (ECs) and …
limited number in peripheral blood. They can give rise to mature endothelial cells (ECs) and …
Every breath you take: non-invasive real-time oxygen biosensing in two-and three-dimensional microfluidic cell models
Knowledge on the availability of dissolved oxygen inside microfluidic cell culture systems is
vital for recreating physiological-relevant microenvironments and for providing reliable and …
vital for recreating physiological-relevant microenvironments and for providing reliable and …
The inclusion of leukocytes into platelet rich plasma reduces scaffold stability and hinders extracellular matrix remodelling.
Background Scaffolds should have controllable degradation rate and allow cells to produce
their own extracellular matrix. Platelet rich plasma (PRP) is a source of autologous growth …
their own extracellular matrix. Platelet rich plasma (PRP) is a source of autologous growth …
The degradation of gelatin/alginate/fibrin hydrogels is cell type dependent and can be modulated by targeting fibrinolysis
E Boucard, L Vidal, F Coulon, C Mota… - … in bioengineering and …, 2022 - frontiersin.org
In tissue engineering, cell origin is important to ensure outcome quality. However, the impact
of the cell type chosen for seeding in a biocompatible matrix has been less investigated …
of the cell type chosen for seeding in a biocompatible matrix has been less investigated …
Microvascular networks from endothelial cells and mesenchymal stromal cells from adipose tissue and bone marrow: a comparison
K Pill, J Melke, S Mühleder, M Pultar… - … in bioengineering and …, 2018 - frontiersin.org
A promising approach to overcome hypoxic conditions in tissue engineered constructs is to
use the potential of endothelial cells (EC) to form networks in vitro when co-cultured with a …
use the potential of endothelial cells (EC) to form networks in vitro when co-cultured with a …
Engineering of three-dimensional pre-vascular networks within fibrin hydrogel constructs by microfluidic control over reciprocal cell signaling
Reengineering functional vascular networks in vitro remains an integral part in tissue
engineering, since the incorporation of non-perfused tissues results in restricted nutrient …
engineering, since the incorporation of non-perfused tissues results in restricted nutrient …
Human-based fibrillar nanocomposite hydrogels as bioinstructive matrices to tune stem cell behavior
The extracellular matrix (ECM)-biomimetic fibrillar structure of platelet lysate (PL) gels along
with their enriched milieu of biomolecules has drawn significant interest in regenerative …
with their enriched milieu of biomolecules has drawn significant interest in regenerative …
Optimization of vascularized intestinal organoid model
Vasculature is crucial for maintaining organ homeostasis and metabolism. Although 3D
organoids can mimic organ structures and patterns, they still lack vascular systems, limiting …
organoids can mimic organ structures and patterns, they still lack vascular systems, limiting …
[HTML][HTML] Extracellular matrix profiling and disease modelling in engineered vascular smooth muscle cell tissues
Aortic smooth muscle cells (SMCs) have an intrinsic role in regulating vessel homeostasis
and pathological remodelling. In two-dimensional (2D) cell culture formats, however, SMCs …
and pathological remodelling. In two-dimensional (2D) cell culture formats, however, SMCs …