Cyanobacterial Harmful Algal Bloom Toxin Microcystin and Increased Vibrio Occurrence as Climate-Change-Induced Biological Co-Stressors: Exposure and Disease …
S Chatterjee, M More - Toxins, 2023 - mdpi.com
The effects of global warming are not limited to rising global temperatures and have set in
motion a complex chain of events contributing to climate change. A consequence of global …
motion a complex chain of events contributing to climate change. A consequence of global …
Oxidative stress, reductive stress and antioxidants in vascular pathogenesis and aging
M Mladenov, L Lubomirov, O Grisk, D Avtanski… - Antioxidants, 2023 - mdpi.com
This review is focused on the mechanisms that regulate health, disease and aging redox
status, the signal pathways that counteract oxidative and reductive stress, the role of food …
status, the signal pathways that counteract oxidative and reductive stress, the role of food …
Mechanistic and therapeutic role of NLRP3 inflammasome in the pathogenesis of Alzheimer's disease
D Jha, ENTP Bakker, R Kumar - Journal of neurochemistry, 2023 - Wiley Online Library
Abstract Alzheimer's disease (AD), a progressive neurodegenerative disorder, has emerged
as the most common form of dementia in the elderly. Several pathological hallmarks have …
as the most common form of dementia in the elderly. Several pathological hallmarks have …
Freshwater cyanobacterial toxins, cyanopeptides and neurodegenerative diseases
Cyanobacteria produce a wide range of structurally diverse cyanotoxins and bioactive
cyanopeptides in freshwater, marine, and terrestrial ecosystems. The health significance of …
cyanopeptides in freshwater, marine, and terrestrial ecosystems. The health significance of …
The role of the NLRP3 inflammasome in mediating glomerular and tubular injury in diabetic nephropathy
BM Williams, CL Cliff, K Lee, PE Squires… - Frontiers in …, 2022 - frontiersin.org
The NOD-like receptor protein 3 (NLRP3) inflammasome is a multi-protein signalling
complex integral to the chronic inflammatory response, activated in response to sterile and …
complex integral to the chronic inflammatory response, activated in response to sterile and …
A new identity of microcystins: Environmental endocrine disruptors? An evidence-based review
S Zhang, H Liu, X Du, X Chen, P Petlulu, Z Tian… - Science of The Total …, 2022 - Elsevier
Microcystins (MCs) are widely distributed cyanobacterial toxins in eutrophic waters. At
present, the endocrine-disrupting effects of MCs have been extensively studied, but whether …
present, the endocrine-disrupting effects of MCs have been extensively studied, but whether …
Chronic microcystin-LR-induced α-synuclein promotes neuroinflammation through activation of the NLRP3 inflammasome in microglia
M Yan, H Jin, C Pan, X Han - Molecular Neurobiology, 2023 - Springer
Abstract Microcystin-LR (MC-LR) has been confirmed to cause blood–brain barrier
disruption and enter the brain tissue, resulting in non-negligible toxic effects. However, the …
disruption and enter the brain tissue, resulting in non-negligible toxic effects. However, the …
[HTML][HTML] First insights into region-specific lipidome alterations of prefrontal cortex and hippocampus of mice exposed chronically to microcystins
Microcystins (MCs), a group of most widespread freshwater cyanotoxins that possess strong
neurotoxicity, can adversely affect brain structures and functions and are linked to …
neurotoxicity, can adversely affect brain structures and functions and are linked to …
Neurofilament light chain and S100B serum levels are associated with disease severity and outcome in patients with aneurysmal subarachnoid hemorrhage
Z Zhou, J Zeng, S Yu, Y Zhao, X Yang, Y Zhou… - Frontiers in …, 2022 - frontiersin.org
Objectives Serum neurofilament light chain (NfL) is a biomarker for neuroaxonal damage,
and S100B is a blood marker for cerebral damage. In the present study, we investigated the …
and S100B is a blood marker for cerebral damage. In the present study, we investigated the …
Prior exposure to microcystin alters host gut resistome and is associated with dysregulated immune homeostasis in translatable mouse models
A strong association between exposure to the common harmful algal bloom toxin
microcystin and the altered host gut microbiome has been shown. We tested the hypothesis …
microcystin and the altered host gut microbiome has been shown. We tested the hypothesis …