Melatonin, a product of tryptophan metabolism via serotonin, is a molecule with an indole
backbone that is widely produced by bacteria, unicellular eukaryotic organisms, plants, fungi …

This article discusses data showing that mammals, including humans, have two sources of
melatonin that exhibit different functions. The best-known source of melatonin, herein …

Human skin aging is associated with functional deterioration on multiple levels of
physiology, necessitating the development of effective skin senotherapeutics. The well …

哺乳动物中褪黑素(melatonin) 主要是由松果体分泌的一种内源性吲哚胺, 含有5-甲氧基和N-
乙酰基侧链两个关键官能团, 以此决定其特异性和双亲性. 近年来, 褪黑素及其代谢产物被认为 …

Abstract Background Ultraviolet-B (UVB) radiation is the leading environmental cause of
skin damage and photoaging. The epidermis and dermis layers of the skin mainly absorb …

Melatonin and sericin exhibit antioxidant properties and may be useful in topical wound
healing patches by maintaining redox balance, cell integrity, and regulating the inflammatory …

The percentage of the total amount of melatonin produced in vertebrates that comes from the
pineal is small (likely< 5%) but, nevertheless, functionally highly noteworthy. The …