Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …

Viral pathologies encompass activation of pro-oxidative pathways and inflammatory burst.
Alleviating overproduction of reactive oxygen species and cytokine storm in COVID-19 is …

The recent coronavirus disease 2019 (COVID-19) pandemic was caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is characterized by …

The SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2), and the disease
it causes (COVID-19), have had a profound impact on global human society and threaten to …

Highlights•Myocardial damage is a typical cardiac manifestation following SARS-CoV-2
infection.•Mechanisms include inflammation, oxidative stress, innate immune response …

Abstract SARS-CoV-2 virus spike (S) protein is an envelope protein responsible for binding
to the ACE2 receptor, driving subsequent entry into host cells. The existence of multiple …

Using molecular dynamics simulations, the protein–protein interactions of the receptor-
binding domain of the wild-type and seven variants of the severe acute respiratory syndrome …

Abstract Objectives Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2
infection is associated with lower plasma glutathione (GSH) levels due to oxidative stress …

After three years of the SARS-CoV-2 pandemic, the search and availability of relatively low-
cost benchtop therapeutics for people not at high risk for a severe disease are still ongoing …