The potential for microRNA therapeutics and clinical research
J Hanna, GS Hossain, J Kocerha - Frontiers in genetics, 2019 - frontiersin.org
As FDA-approved small RNA drugs start to enter clinical medicine, ongoing studies for the
microRNA (miRNA) class of small RNAs expand its preclinical and clinical research …
microRNA (miRNA) class of small RNAs expand its preclinical and clinical research …
miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
S Zhou, J Jin, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
world. Although considerable progress has been made in the diagnosis, treatment and …
world. Although considerable progress has been made in the diagnosis, treatment and …
Identifying circulating microRNAs as biomarkers of cardiovascular disease: a systematic review
R Navickas, D Gal, A Laucevičius… - Cardiovascular …, 2016 - academic.oup.com
The aim of the present study is to identify microRNAs (miRs) with high potential to be used
as biomarkers in plasma and/or serum to clinically diagnose, or provide accurate prognosis …
as biomarkers in plasma and/or serum to clinically diagnose, or provide accurate prognosis …
Specific miRNA disease biomarkers in blood, serum and plasma: challenges and prospects
Significant effort has been devoted to discovering microRNA (miRNA) disease biomarkers.
In particular, miRNAs in whole blood or specific blood components are candidates for …
In particular, miRNAs in whole blood or specific blood components are candidates for …
[HTML][HTML] MicroRNA and cardiovascular diseases
HA Çakmak, M Demir - Balkan medical journal, 2020 - ncbi.nlm.nih.gov
Cardiovascular diseases are one of the most common causes of death in both developing
and developed countries worldwide. Even though there have been improvements in primary …
and developed countries worldwide. Even though there have been improvements in primary …
Methodological challenges in utilizing mi RNA s as circulating biomarkers
L Moldovan, KE Batte, J Trgovcich… - Journal of cellular …, 2014 - Wiley Online Library
Micro RNA s (mi RNA s) have emerged as important regulators in the post‐transcriptional
control of gene expression. The discovery of their presence not only in tissues but also in …
control of gene expression. The discovery of their presence not only in tissues but also in …
Novel methodologies for biomarker discovery in atherosclerosis
IE Hoefer, S Steffens, M Ala-Korpela… - European heart …, 2015 - academic.oup.com
Identification of subjects at increased risk for cardiovascular events plays a central role in the
worldwide efforts to improve prevention, prediction, diagnosis, and prognosis of …
worldwide efforts to improve prevention, prediction, diagnosis, and prognosis of …
Stem cell therapy for ischemic heart diseases
H Yu, K Lu, J Zhu, J Wang - British medical bulletin, 2017 - academic.oup.com
Introduction Ischemic heart diseases, especially the myocardial infarction, is a major hazard
problem to human health. Despite substantial advances in control of risk factors and …
problem to human health. Despite substantial advances in control of risk factors and …
MicroRNAs expression profiles in cardiovascular diseases
E Bronze-da-Rocha - BioMed research international, 2014 - Wiley Online Library
The current search for new markers of cardiovascular diseases (CVDs) is explained by the
high morbidity and mortality still observed in developed and developing countries due to …
high morbidity and mortality still observed in developed and developing countries due to …
Non-coding RNAs in cardiac remodeling and heart failure
R Kumarswamy, T Thum - Circulation research, 2013 - Am Heart Assoc
Heart failure is a leading cause of death in industrialized nations especially in an aging
population. The recent improvements in cardiac revascularization therapy reduced death …
population. The recent improvements in cardiac revascularization therapy reduced death …