Bone quality assessment techniques: geometric, compositional, and mechanical characterization from macroscale to nanoscale

HB Hunt, E Donnelly - Clinical reviews in bone and mineral metabolism, 2016 - Springer
This review presents an overview of the characterization techniques available to
experimentally evaluate bone quality, defined as the geometric and material factors that …

Nuclear magnetic resonance (NMR)‐based metabolomics for cancer research

R Ranjan, N Sinha - NMR in Biomedicine, 2019 - Wiley Online Library
Nuclear magnetic resonance (NMR) has emerged as an effective tool in various spheres of
biomedical research, amongst which metabolomics is an important method for the study of …

Nano-hydroxyapatite bone substitute functionalized with bone active molecules for enhanced cranial bone regeneration

AK Teotia, DB Raina, C Singh, N Sinha… - … applied materials & …, 2017 - ACS Publications
The aim of this study was to synthesize and characterize a nano-hydroxyapatite (nHAP) and
calcium sulfate bone substitute (NC) for cranioplasty. The NC was functionalized with low …

Ex vivo exposure to calcitonin or raloxifene improves mechanical properties of diseased bone through non-cell mediated mechanisms

RK Surowiec, R Saldivar, RK Rai, CE Metzger… - Bone, 2023 - Elsevier
Raloxifene (RAL) reduces clinical fracture risk despite modest effects on bone mass and
density. This reduction in fracture risk may be due to improved material level-mechanical …

Molecular differences in collagen organization and in organic-inorganic interfacial structure of bones with and without osteocytes

R Nanda, S Hazan, K Sauer, V Aladin… - Acta Biomaterialia, 2022 - Elsevier
Bone is a fascinating biomaterial composed mostly of type-I collagen fibers as an organic
phase, apatite as an inorganic phase, and water molecules residing at the interfaces …

Lysozyme is Sterically Trapped Within the Silica Cage in Bioinspired Silica–Lysozyme Composites: A Multi-Technique Understanding of Elusive Protein–Material …

F Bruno, L Gigli, G Ferraro, A Cavallo, VK Michaelis… - Langmuir, 2022 - ACS Publications
Lysozyme is widely known to promote the formation of condensed silica networks from
solutions containing silicic acid, in a reproducible and cost-effective way. However, little is …

[PDF][PDF] NMR-active nuclei for biological and biomedical applications

SG Patching - Journal of Diagnostic Imaging in Therapy, 2016 - openmedscience.com
Nuclear magnetic resonance (NMR) spectroscopy is a principal well-established technique
for analysis of chemical, biological, food and environmental samples. This article provides …

Mechanistic insights into the structural stability of collagen-containing biomaterials such as bones and cartilage

N Tiwari, S Wi, F Mentink-Vigier… - The Journal of Physical …, 2021 - ACS Publications
Structural stability of various collagen-containing biomaterials such as bones and cartilage
is still a mystery. Despite the spectroscopic development of several decades, the detailed …

Solid-state NMR studies on the organic matrix of bone

HD Xue, Y Yin, T He, H Song, J Li, X Kong - Nano Research, 2023 - Springer
Bone is a hierarchical architecture that consists of both inorganic and organic components.
The organic components, including collagen and numerous non-collagenous biomolecules …

Solid-state NMR spectroscopy: the magic wand to view bone at nanoscopic resolution

KH Mroue, A Viswan, N Sinha… - Annual Reports on NMR …, 2017 - Elsevier
The unique potential of solid-state NMR (SSNMR) spectroscopy to provide atomistic-scale
piercing insights into the structure and dynamics of complex biomaterials, such as the …