High‐throughput metabolomics by 1D NMR
Metabolomics deals with the whole ensemble of metabolites (the metabolome). As one of
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …
NMR and pattern recognition methods in metabolomics: from data acquisition to biomarker discovery: a review
Metabolomics is the discipline where endogenous and exogenous metabolites are
assessed, identified and quantified in different biological samples. Metabolites are crucial …
assessed, identified and quantified in different biological samples. Metabolites are crucial …
Bioinformatics tools for mass spectroscopy-based metabolomic data processing and analysis
M Sugimoto, M Kawakami, M Robert… - Current …, 2012 - ingentaconnect.com
Biological systems are increasingly being studied in a holistic manner, using omics
approaches, to provide quantitative and qualitative descriptions of the diverse collection of …
approaches, to provide quantitative and qualitative descriptions of the diverse collection of …
Cell culture metabolomics: applications and future directions
M Čuperlović-Culf, DA Barnett, AS Culf, I Chute - Drug discovery today, 2010 - Elsevier
Metabolomics represents a global quantitative assessment of metabolites within a biological
system. The metabolic analysis of cell cultures has many potential applications and …
system. The metabolic analysis of cell cultures has many potential applications and …
NMR in metabolomics: From conventional statistics to machine learning and neural network approaches
NMR measurements combined with chemometrics allow achieving a great amount of
information for the identification of potential biomarkers responsible for a precise metabolic …
information for the identification of potential biomarkers responsible for a precise metabolic …
Multivariate analysis of NMR‐based metabolomic data
J Debik, M Sangermani, F Wang… - NMR in …, 2022 - Wiley Online Library
Nuclear magnetic resonance (NMR) spectroscopy allows for simultaneous detection of a
wide range of metabolites and lipids. As metabolites act together in complex metabolic …
wide range of metabolites and lipids. As metabolites act together in complex metabolic …
Bioinformatics tools for cancer metabolomics
It is well known that significant metabolic change take place as cells are transformed from
normal to malignant. This review focuses on the use of different bioinformatics tools in …
normal to malignant. This review focuses on the use of different bioinformatics tools in …
Metabolic adaptation of human pathogenic and related nonpathogenic bacteria to extra-and intracellular habitats
TM Fuchs, W Eisenreich, J Heesemann… - FEMS microbiology …, 2012 - academic.oup.com
Most bacteria pathogenic for humans have closely related nonpathogenic counterparts that
live as saprophytes, commensals or even symbionts (mutualists) in similar or different …
live as saprophytes, commensals or even symbionts (mutualists) in similar or different …
Non-targeted metabolomic biomarkers and metabotypes of type 2 diabetes: A cross-sectional study of PREDIMED trial participants
M Urpi-Sarda, E Almanza-Aguilera, R Llorach… - Diabetes & …, 2019 - Elsevier
Aim To characterize the urinary metabolomic fingerprint and multi-metabolite signature
associated with type 2 diabetes (T2D), and to classify the population into metabotypes …
associated with type 2 diabetes (T2D), and to classify the population into metabotypes …
Quantification and statistical significance analysis of group separation in NMR-based metabonomics studies
AM Goodpaster, MA Kennedy - Chemometrics and Intelligent Laboratory …, 2011 - Elsevier
Currently, no standard metrics are used to quantify cluster separation in PCA or PLS-DA
scores plots for metabonomics studies or to determine if cluster separation is statistically …
scores plots for metabonomics studies or to determine if cluster separation is statistically …