Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer
QF Han, WJ Li, KS Hu, J Gao, WL Zhai, JH Yang… - Molecular cancer, 2022 - Springer
Exosomes are well-known key mediators of intercellular communication and contribute to
various physiological and pathological processes. Their biogenesis involves four key steps …
various physiological and pathological processes. Their biogenesis involves four key steps …
A review of the regulatory mechanisms of extracellular vesicles-mediated intercellular communication
Extracellular vesicles (EVs) are small, membrane-bound structures that are released from
cells into the surrounding environment. These structures can be categorized as exosomes …
cells into the surrounding environment. These structures can be categorized as exosomes …
Exosomes as smart drug delivery vehicles for cancer immunotherapy
H Zhang, S Wang, M Sun, Y Cui, J Xing… - Frontiers in …, 2023 - frontiersin.org
Exosomes (Exos) as drug delivery vehicles have been widely used for cancer
immunotherapy owing to their good biocompatibility, low toxicity, and low immunogenicity …
immunotherapy owing to their good biocompatibility, low toxicity, and low immunogenicity …
The distinct roles of exosomes in innate immune responses and therapeutic applications in cancer
The innate immune system is one of the major constituents of the host's defense against
invading pathogens and extracellular vesicles (EVs) are involved in regulating its …
invading pathogens and extracellular vesicles (EVs) are involved in regulating its …
Exosomes: a potential diagnostic and treatment modality in the quest for counteracting cancer
G Patel, TG Agnihotri, M Gitte, T Shinde, SS Gomte… - Cellular Oncology, 2023 - Springer
Background Exosomes are nanosized bio vesicles formed when multivesicular bodies and
the plasma membrane merge and discharge into bodily fluids. They are well recognized for …
the plasma membrane merge and discharge into bodily fluids. They are well recognized for …
Exosomes and exosome-loaded scaffolds: characterization and application in modern regenerative medicine
Exosomes (EXOs) are extracellular vesicles derived from the endosome. These
heterogeneous nanoparticles (30–150 nm) are secreted from various cells and play …
heterogeneous nanoparticles (30–150 nm) are secreted from various cells and play …
Engineered exosomes for tumor-targeted drug delivery: a focus on genetic and chemical functionalization
Cancer is the main cause of death worldwide. The limitations in traditional cancer therapies
provoked the advance and use of several nanotechnologies for more effective and nontoxic …
provoked the advance and use of several nanotechnologies for more effective and nontoxic …
Exosomal noncoding RNAs in prostate cancer
Prostate cancer (PCa) is the second most common cancer and the fifth leading cause of
mortality among men. The recurrent reports of false-positive results of common PCa …
mortality among men. The recurrent reports of false-positive results of common PCa …
Therapeutic application of mesenchymal stem cells derived exosomes in neurodegenerative diseases: a focus on non-coding RNAs cargo, drug delivery potential …
Despite the massive efforts advanced over recent years in emerging therapies for
neurodegenerative diseases, effective treatment for these diseases is still an urgent need …
neurodegenerative diseases, effective treatment for these diseases is still an urgent need …
Harnessing normal and engineered mesenchymal stem cells derived exosomes for cancer therapy: opportunity and challenges
There remains a vital necessity for new therapeutic approaches to combat metastatic
cancers, which cause globally over 8 million deaths per year. Mesenchymal stem cells …
cancers, which cause globally over 8 million deaths per year. Mesenchymal stem cells …