Acquired von Willebrand syndrome associated with cardiovascular diseases

H Horiuchi, T Doman, K Kokame, Y Saiki… - … of atherosclerosis and …, 2019 - jstage.jst.go.jp
304 lets, GPIIb/IIIa (integrin αIIbβ3) that is abundantly present on platelets changes its
conformation to allow it to bind its ligands, VWF and fibrinogen20, 21). A part (~ 30%) of …

Mechanical circulatory support: balancing bleeding and clotting in high-risk patients

L Baumann Kreuziger… - Hematology 2014, the …, 2015 - ashpublications.org
Mechanical circulatory support (MCS) provides a bridge to heart transplant in children and
adults with life-threatening heart failure and sustains patients ineligible for transplant …

Acquired von Willebrand syndrome in paediatric patients during mechanical circulatory support

R Kubicki, B Stiller, J Kroll, M Siepe… - European Journal of …, 2019 - academic.oup.com
OBJECTIVES Bleeding signs can become life-threatening complications in patients on
mechanical circulatory support (MCS). Clinical phenotyping and comprehensive analyses of …

Pediatric acquired von Willebrand disease with berlin heart EXCOR ventricular assist device support

N Gossai, NM Brown, R Ameduri… - World Journal for …, 2016 - journals.sagepub.com
Background: The balance of hemostasis and anticoagulation is a concern for patients
dependent upon ventricular assist devices (VADs). Bleeding is a common complication with …

In vitro hemocompatibility evaluation of ventricular assist devices in pediatric flow conditions: a benchmark study

CHH Chan, S Diab, K Moody, OH Frazier… - Artificial …, 2018 - Wiley Online Library
Abstract Development of pediatric ventricular assist devices (VADs) has significantly lagged
behind that of adult devices. This frustrating reality is reflected by the fact that the Berlin …

Pathophysiology, epidemiology, and management of acquired von Willebrand syndrome

U Budde, AB Federici - … of von Willebrand Disease: Basic and …, 2024 - Wiley Online Library
An acquired bleeding disorder with clinical and laboratory features like the inherited von
Willebrand disease (VWD) has been reported since 1968. Such a disorder was defined as …

Management of a pediatric patient with a left ventricular assist device and symptomatic acquired von Willebrand syndrome presenting for orthotopic heart transplant

KM Flannery, K Kamra, K Maeda… - Seminars in …, 2020 - journals.sagepub.com
We present the successful perioperative management of an 11-year-old patient presenting
for heart transplant with a left ventricular assist device, symptomatic acquired von Willebrand …

[PDF][PDF] Advantage of recombinant von Willebrand factor for peri‐operative management in paediatric acquired von Willebrand syndrome

AC Weyand, R Jesudas, SW Pipe - 2018 - deepblue.lib.umich.edu
Dear Editors, A 2-year-old African American male child with pulmonary valve stenosis
sustained a skull fracture and large epidural haemorrhage after a fall. He underwent multiple …

[HTML][HTML] Distinct Mechanisms of IgM Antibody-Mediated Acquired von Willebrand Syndrome and Successful Treatment with Recombinant von Willebrand Factor in …

M Höpting, U Budde, A Tiede, M Grube, J Hahn… - Acta …, 2022 - karger.com
Abstract Acquired von Willebrand Syndrome (AVWS) is a rare coagulation disorder which
can be associated with IgM paraproteinaemia. Recently, recombinant von Willebrand factor …

Space and time resolved detection of platelet activation and von Willebrand Factor conformational changes in deep suspensions

J Biasetti, K Sampath, A Cortez, A Azhir… - International Journal …, 2017 - Wiley Online Library
Tracking cells and proteins' phenotypic changes in deep suspensions is critical for the direct
imaging of blood‐related phenomena in in vitro replica of cardiovascular systems and blood …