The cancerous process is result of disturbed cell function. This is due to the accumulation of
many genetic and epigenetic changes within the cell, expressed in the accumulation of …

Astrocytes are specialized glial cells that outnumber neurons by over fivefold. They
contiguously tile the entire central nervous system (CNS) and exert many essential complex …

Mounting evidence indicates that Merkel cell polyomavirus (MCV), a circular double-
stranded DNA virus, is a causal factor underlying a highly lethal form of skin cancer known …

The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In
humans, polyomaviruses can cause infections of the central nervous system, urinary tract …

Today the human polyomavirus (HPyV) family consists of 10 members, BK virus (BKV) and
JC virus (JCV) isolated 40 years ago and the more recently identified KI virus (KIPyV), WU …

Objective: To determine the feasibility of next-generation sequencing (NGS) microbiome
approaches in the diagnosis of infectious disorders in brain or spinal cord biopsies in …

The name of the family Polyomaviridae, derives from the early observation that cells infected
with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised …

Polyomaviruses are small, non-enveloped viruses with a circular double-stranded DNA
genome. Using a generic polyomavirus PCR targeting the VP1 major structural protein …

Glioblastoma is a highly aggressive malignant tumor involving glial cells in the human brain.
We used high-throughput sequencing to comprehensively profile the small RNAs expressed …

Merkel cell carcinoma (MCC) is a rare and aggressive form of skin cancer. In at least 80% of
all MCC, Merkel cell polyomavirus (MCPyV) DNA has undergone clonal integration into the …