Early degeneration of both dopaminergic and serotonergic axons–a common mechanism in Parkinson's disease

J Grosch, J Winkler, Z Kohl - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Motor symptoms in Parkinson's disease (PD) are tightly linked to the degeneration of
substantia nigra dopaminergic neurons and their projections into the striatum. Moreover, a …

Non-motor symptoms of Parkinson's disease and their impact on quality of life in a cohort of Moroccan patients

H Tibar, K El Bayad, A Bouhouche… - Frontiers in …, 2018 - frontiersin.org
Background Non-motor symptoms (NMSs) are a real burden in Parkinson's disease (PD).
They may appear in early pre-symptomatic stage as well as throughout the disease course …

Interventions within the scope of occupational therapy to improve activities of daily living, rest, and sleep in people with Parkinson's disease: A systematic review

BM Doucet, I Franc, EG Hunter - The American Journal of …, 2021 - research.aota.org
Interventions Within the Scope of Occupational Therapy to Improve Activities of Daily Living,
Rest, and Sleep in People With Parkinson’s Disease: A Systematic Review | The American …

Nonmotor symptoms evolution during 24 months of bilateral subthalamic stimulation in Parkinson's disease

HS Dafsari, M Silverdale, M Strack, A Rizos… - Movement …, 2018 - Wiley Online Library
Background: The objective of this study was to investigate 24‐month of effects of bilateral
subthalamic nucleus (STN) deep brain stimulation (DBS) on nonmotor symptoms in …

Comparison of associations between MIND and Mediterranean diet scores with patient-reported outcomes in Parkinson's disease

DJ Fox, SJH Park, LK Mischley - Nutrients, 2022 - mdpi.com
The Mediterranean (MEDI) and Mediterranean-DASH Intervention for Neurodegenerative
Delay (MIND) diets have been associated with a reduced risk of Parkinson's disease (PD) …

Role of resilience and social support in alleviating depression in patients receiving maintenance hemodialysis

YM Liu, HJ Chang, RH Wang, LK Yang… - … and clinical risk …, 2018 - Taylor & Francis
Background Patients who undergo hemodialysis encounter challenges including role
changes, physical degeneration, and difficulty in performing activities of daily living (ADLs) …

A comprehensive phenotype of non-motor impairments and distribution of alpha-synuclein deposition in parkinsonism-induced mice by a combination injection of …

NR Han, YK Kim, S Ahn, TY Hwang, H Lee… - Frontiers in aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is characterized by non-motor symptoms as well as motor deficits.
The non-motor symptoms rarely appear individually and occur simultaneously with motor …

Motor and non-motor function predictors of mortality in Parkinson's disease

P Bugalho, F Ladeira, R Barbosa, JP Marto… - Journal of neural …, 2019 - Springer
Doubts persist regarding the influence of Parkinson's disease (PD) on mortality. Our
objective was to assess mortality rates in a prospectively followed cohort of PD patients and …

Cognitive complaints in Parkinson's disease patients: from subjective cognitive complaints to dementia and affective disorders

RP Barbosa, MD Mendonça, AP Caetano… - Journal of Neural …, 2019 - Springer
Subjective cognitive complaints (SCC) are frequent in elderly populations. PD patients
report SCC more often than healthy controls. The association between SCC, objective …

Progression in parkinson's disease: variation in motor and non‐motor symptoms severity and predictors of decline in cognition, motor function, disability, and health …

P Bugalho, F Ladeira, R Barbosa… - Movement Disorders …, 2021 - Wiley Online Library
Background Parkinson's disease (PD) is multi‐symptom disease with variable progression.
Objectives We performed a longitudinal study to address the evolution of motor symptoms …