All mammalian uteri contain glands in the endometrium that develop only or primarily after
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …

Abstract Internal N 6-methyladenosine (m6A) modification is widespread in messenger
RNAs (mRNAs) and is catalyzed by heterodimers of methyltransferase-like protein 3 (Mettl3) …

The mammalian oviduct is a dynamic organ where important events such as final maturation
of oocytes, transport of gametes, sperm capacitation, fertilization, embryo development, and …

Uterine glands are essential for pregnancy establishment. By employing forkhead box A2
(FOXA2)-deficient mouse models coupled with leukemia inhibitory factor (LIF) repletion, we …

Abstract ARID1A and PI3-Kinase (PI3K) pathway alterations are common in neoplasms
originating from the uterine endometrium. Here we show that monoallelic loss of ARID1A in …

Estrogen and progesterone, acting through their cognate receptors the estrogen receptor α
(ERα) and the progesterone receptor (PR) respectively, regulate uterine biology. Using rapid …

Successful embryo implantation requires a receptive endometrium. Poor uterine receptivity
can account for implantation failure in women who experience recurrent pregnancy loss or …

Establishment of pregnancy is a critical event, and failure of embryo implantation and
stromal decidualization in the uterus contribute to significant numbers of pregnancy losses in …

Endometriosis affects 1 in 10 women and is characterized by the presence of abnormal
endometrium at ectopic sites. ARID1A mutations are observed in deeply invasive forms of …

Mammalian pregnancy depends on the ability of the uterus to support embryo implantation.
Previous studies reveal the Sox17 gene as a downstream target of the Pgr-Gata2 …