Introduction: Generalized pustular psoriasis (GPP) is a rare, severe relapsing/remitting,
multisystem disease that can be difficult to treat. Recent clinical, histological, and genetic …

Generalized pustular psoriasis (GPP) is a rare, severe form of pustular psoriasis
characterized by widespread, recurrent episodes of neutrophil-rich pustule formation in the …

Psoriasis is a common, chronic papulosquamous skin disease occurring worldwide,
presenting at any age, and leading to a substantial burden for individuals and society. It is …

Background Spesolimab is an anti-interleukin-36 receptor monoclonal antibody approved to
treat generalised pustular psoriasis (GPP) flares. We aimed to assess the efficacy and safety …

Generalized pustular psoriasis (GPP) is a rare auto‐inflammatory skin disease characterised
by acute episodes of sterile pustule formation. Diagnosis and treatment of the disease have …

Introduction Generalized pustular psoriasis (GPP) is a rare, severe, clinically heterogeneous
disease characterized by flares of widespread, noninfectious, macroscopically visible …

The IL-36 family of cytokines includes three pro-inflammatory agonists (IL-36α, IL-36β, and
IL-36γ) and a receptor antagonist (IL-36Ra), which bind and signal through a heterodimeric …

Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Theme issue: Psoriasis loci. Despite the complex correlation structure across the MHC due
to extensive linkage disequilibrium (Box 1)(16), HLA-C* 06: 02 is now confidently …

Psoriasis is a chronic inflammatory skin condition that has a fairly wide range of clinical
presentations. Plaque psoriasis, which is the most common manifestation of psoriasis, is …