The regulatory network of cyclic GMP-AMP synthase-stimulator of interferon genes pathway in viral evasion

T Hu, M Pan, Y Yin, C Wang, Y Cui… - Frontiers in Microbiology, 2021 - frontiersin.org
Virus infection has been consistently threatening public health. The cyclic GMP-AMP
synthase (cGAS)-Stimulator of Interferon Genes (STING) pathway is a critical defender to …

Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques

L Santus, M Sopena-Rios, R García-Pérez… - Nature …, 2023 - nature.com
Long non-coding RNAs (lncRNAs) are involved in numerous biological processes and are
pivotal mediators of the immune response, yet little is known about their properties at the …

[HTML][HTML] Long non-coding RNAs and immune cells: Unveiling the role in viral infections

D Zhang, M Zhang, L Zhang, W Wang, S Hua… - Biomedicine & …, 2024 - Elsevier
Viral infections present significant challenges to human health, underscoring the importance
of understanding the immune response for effective therapeutic strategies. Immune cell …

Biophysical characterisation of human LincRNA-p21 sense and antisense Alu inverted repeats

MH D'Souza, T Mrozowich, MD Badmalia… - Nucleic acids …, 2022 - academic.oup.com
Abstract Human Long Intergenic Noncoding RNA-p21 (LincRNA-p21) is a regulatory
noncoding RNA that plays an important role in promoting apoptosis. LincRNA-p21 is also …

Long noncoding RNA# 61 exerts a broad anti-influenza a virus effect by its long arm rings

J Hu, L Zhang, X Zheng, G Wang, X Chen, Z Hu… - Antiviral Research, 2023 - Elsevier
Emerging evidence has demonstrated the critical role of long noncoding RNAs (lncRNAs) in
regulating gene expression. However, the functional significance and mechanisms …

[HTML][HTML] Long non-coding RNAs ANRIL, THRIL, and NEAT1 as potential circulating biomarkers of SARS-CoV-2 infection and disease severity

Z Rahni, SM Hosseini, S Shahrokh, MS Niasar… - Virus Research, 2023 - Elsevier
The current outbreak of coronavirus disease 2019 (COVID-19) is a global emergency, as its
rapid spread and high mortality rate, which poses a significant threat to public health. Innate …

Co-regulation of protein coding genes by transcription factor and long non-coding RNA in SARS-CoV-2 infected cells: an in silico analysis

C Saha, S Laha, R Chatterjee, NP Bhattacharyya - Non-coding RNA, 2021 - mdpi.com
Altered expression of protein coding gene (PCG) and long non-coding RNA (lncRNA) have
been identified in SARS-CoV-2 infected cells and tissues from COVID-19 patients. The …

SNHG15 aids SARS-CoV-2 entry via RABL2A

S Pushparaj, C Gandikota, K Vaddadi, Y Liang… - RNA biology, 2023 - Taylor & Francis
ABSTRACT Angiotensin-converting enzyme 2 (ACE2) and several proteins have been
identified as entry factors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

[HTML][HTML] In silico analysis of SARS-CoV-2 genomes: Insights from SARS encoded non-coding RNAs

N Periwal, U Bhardwaj, S Sarma, P Arora… - Frontiers in Cellular and …, 2022 - frontiersin.org
The recent pandemic caused by Severe Acute Respiratory Syndrome Coronavirus-2 has
resulted in enormous deaths around the world. Clues from genomic sequences of parent …

Therapeutic potential of long non-coding RNAs of HIV-1, SARS-CoV-2, and endogenous retroviruses

AV Ruiz Ramírez, E Prado Montes de Oca - Frontiers in Virology, 2022 - frontiersin.org
Long non-protein coding RNAs (lncRNAs, predicted to be up to 200,000 in the human
genome) are nucleic acids of more than 200 nucleotides that not only play primordial roles …