Developments and applications of functional protein microarrays

GD Syu, J Dunn, H Zhu - Molecular & Cellular Proteomics, 2020 - ASBMB
Protein microarrays are crucial tools in the study of proteins in an unbiased, high-throughput
manner, as they allow for characterization of up to thousands of individually purified proteins …

Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection

J Zhang, C Chen, A Li, W Jing, P Sun, X Huang… - Nature …, 2021 - nature.com
Immunotherapies have revolutionized intervention strategies for many primary cancers, but
have not improved the outcomes of glioblastoma multiforme (GBM), which remains one of …

Advances in the development of human protein microarrays

JG Duarte, JM Blackburn - Expert review of proteomics, 2017 - Taylor & Francis
Introduction: High-content protein microarrays in principle enable the functional interrogation
of the human proteome in a broad range of applications, including biomarker discovery …

Anti-cancer auto-antibodies: Roles, applications and open issues

H de Jonge, L Iamele, M Maggi, G Pessino, C Scotti - Cancers, 2021 - mdpi.com
Simple Summary Cancer is one of the main causes of death worldwide and early detection
is crucial for effective treatment. Scientists have therefore focused on the identification of …

Identification of serological biomarkers for early diagnosis of lung cancer using a protein array-based approach

J Pan, G Song, D Chen, Y Li, S Liu, S Hu… - Molecular & Cellular …, 2017 - ASBMB
Lung cancer (LC) remains the leading cause of mortality from malignant tumors worldwide.
Currently, a lack of serological biomarkers for early LC diagnosis is a major roadblock for …

[HTML][HTML] Differentially expressed proteins in glioblastoma multiforme identified with a nanobody-based anti-proteome approach and confirmed by OncoFinder as …

I Jovčevska, N Zupanec, Ž Urlep, A Vranič, B Matos… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Glioblastoma multiforme is the most frequent primary malignancy of the central nervous
system. Despite remarkable progress towards an understanding of tumor biology, there is no …

The plasma peptides of Alzheimer's disease

A Florentinus-Mefailoski, P Bowden, P Scheltens… - Clinical Proteomics, 2021 - Springer
Background A practical strategy to discover proteins specific to Alzheimer's dementia (AD)
may be to compare the plasma peptides and proteins from patients with dementia to normal …

A protein microarray‐based serum proteomic investigation reveals distinct autoantibody signature in colorectal cancer

A Barpanda, C Tuckley, A Ray… - PROTEOMICS …, 2023 - Wiley Online Library
Purpose Colorectal cancer (CRC) has been reported as the second leading cause of cancer
death worldwide. The 5‐year annual survival is around 50%, mainly due to late diagnosis …

Identification of tumor-associated antigens with diagnostic ability of colorectal cancer by in-depth immunomic and seroproteomic analysis

M Garranzo-Asensio, P San Segundo-Acosta… - Journal of …, 2020 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer related death worldwide. Its diagnosis at early stages would significantly improve the …

Development of autoantibody signatures for common cancers

M Kobayashi, H Katayama, JF Fahrmann… - Seminars in …, 2020 - Elsevier
A humoral immune response in the form of autoantibodies to tumor antigens occurs early
during tumor development. Identification of antigens that induce an autoantibody response …