Nucleation of new peptide and protein aggregates on the surfaces of amyloid fibrils of the
same peptide or protein has emerged in the past two decades as a major pathway for both …

Amyloids, fibrillar assembly of (poly) peptide chains, are associated with neurodegenerative
illnesses such as Alzheimer's and Parkinson's diseases, for which there are no cures. The …

Many neurodegenerative diseases are rooted in the activities of amyloid-like proteins which
possess conformations that spread to healthy proteins. These include Alzheimer's disease …

Cell membranes are very complex biological systems including a large variety of lipids and
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …

The accumulation of the amyloid‐β peptides (Aβ) is central to the development of
Alzheimer's disease. The mechanism by which Aβ triggers a cascade of events that leads to …

Interfaces can strongly accelerate or inhibit protein aggregation, destabilizing proteins that
are stable in solution or, conversely, stabilizing proteins that are aggregation-prone …

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease
characterized by the extracellular deposition of amyloid plaques. Investigation into the …

In this article, we consider the role of heterogeneous nucleation in β‐amyloid aggregation.
Heterogeneous nucleation is more common and occurs at lower levels of supersaturation …

The prediction of highly ordered three-dimensional structures of amyloid protein fibrils from
the amino acid sequences of their monomeric self-assembly precursors constitutes a …

Inhibition of amyloid β peptide (Aβ) aggregation is an important goal due to the connection
of this process with Alzheimer's disease. Traditionally, inhibitors were developed with an aim …