Recent advances in chemical reactivity and biological activities of eugenol derivatives

A Abdou, A Elmakssoudi, A El Amrani… - Medicinal Chemistry …, 2021 - Springer
Abstract Eugenol (4-allyl-2-methoxyphenol) is a volatile phenolic bioactive compound
derived from a natural resource. This compound has been identified in several aromatic …

[HTML][HTML] The multiple faces of eugenol. A versatile starting material and building block for organic and bio-organic synthesis and a convenient precursor toward bio …

TS Kaufman - Journal of the Brazilian Chemical Society, 2015 - SciELO Brasil
Phenylpropenes are produced by plants as part of their defense strategy against
microorganisms and animals, and also as floral attractants of pollinators. Eugenol, the main …

Oxazine Ring-Related Vibrational Modes of Benzoxazine Monomers Using Fully Aromatically Substituted, Deuterated, 15N Isotope Exchanged, and Oxazine-Ring …

L Han, D Iguchi, P Gil, TR Heyl… - The Journal of …, 2017 - ACS Publications
Polymerization of benzoxazine resins is indicated by the disappearance of a 960–900 cm–1
band in infrared spectroscopy (IR). Historically, this band was assigned to the C–H out-of …

[PDF][PDF] Outlooks on medicinal properties of eugenol and its synthetic derivatives

RS Bendre, JD Rajput, SD Bagul… - Nat Prod Chem …, 2016 - researchgate.net
Eugenol is found in essential oils of many plants. It belongs to a class of naturally occurring
phenolic monoterpenoids, chemically it is an allyl chain-substituted guaiacol. Eugenol is a …

Tailored functionalization of natural phenols to improve biological activity

B Floris, P Galloni, V Conte, F Sabuzi - Biomolecules, 2021 - mdpi.com
Phenols are widespread in nature, being the major components of several plants and
essential oils. Natural phenols' anti-microbial, anti-bacterial, anti-oxidant, pharmacological …

Perspectives on medicinal properties of natural phenolic monoterpenoids and their hybrids

JD Rajput, SD Bagul, UD Pete, CM Zade, SB Padhye… - Molecular Diversity, 2018 - Springer
Carvacrol, thymol and eugenol belong to a class of naturally presenting phenols with a ten-
carbon unit, which are present in essential oils of many plants. These versatile molecules …

Discovery of eugenol-derived drug candidates for the treatment of COVID-19 by applying molecular docking, molecular dynamics, and pharmacokinetic analysis

N Mounadi, H Nour, A Errougui, M Talbi… - Physical Chemistry …, 2024 - physchemres.org
Given the pandemic of COVID-19, the new generation of coronavirus noted SARS-CoV-2
still remains a global health threat to this day, the absence of effective and reliable …

Probing the Mechanism of Action of Bis (phenolato) Amine (ONO Donor Set) Titanium (IV) Anticancer Agents

M Musa, M Abid, TD Bradshaw… - Journal of Medicinal …, 2024 - ACS Publications
The need for anticancer therapies that overcome metallodrug resistance while minimizing
adverse toxicities is targeted, herein, using titanium coordination complexes. Octahedral …

Molecular docking studies of synthesized pyridazinone scaffolds as non-nucleoside reverse transcriptase inhibitors (NNRTIs)

M Yusuf, O Abdulaziz, A Aljuaid… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Abstract Pyridazinone derivatives, 6-aryl-pyridazinone (2a–f) and 2-(N-substituted)-6-aryl-
pyridazinone (3a–h) derivatives were synthesized and assessed for cytotoxicity action using …

1, 3‐Oxazine as a promising scaffold for the development of biologically active lead molecules

N Gupta, V Saini, SM Basavarajaiah, MO Dar… - …, 2023 - Wiley Online Library
Heterocyclic compounds form an important part of wide range of biologically active
molecules. The heteroatom provides them specificity for various receptors. 1, 3‐oxazine has …