Preshaw PM, Taylor JJ. How has research into cytokine interactions and their role in driving
immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011; …

Periodontal disease is the major cause of adult tooth loss and is commonly characterized by
a chronic inflammation caused by infection of oral bacteria. Porphyromonas gingivalis (P …

Rheumatoid arthritis and periodontitis are inflammatory diseases modulated by
proinflammatory cytokines [eg interleukin (IL-1) 1 and tumour necrosis factor α], which …

Objective: To establish and characterise a rat model of periodontitis that reiterates the
features of human disease. Methods: Periodontal inflammation was induced by a single …

The distributions of the bi‐allelic interleukin‐1β+ 3953 and tumor necrosis factor‐σ− 308
genotypes were determined in 20 patients with advanced adult periodontitis, 20 patients …

There are wide variations of gene expression and strikingly different responses to
extracellular signals among different fibroblast populations. This has prompted a large …

The physiological inflammatory response can provide an effective mechanism for delivering
the baby at the time of parturition. We characterized the mechanisms by which hyaluronic …

Tumor necrosis factor alpha (TNF‐α) is a proinflammatory cytokine that is thought to play a
role in the pathogenesis of periodontal disease. TNF‐α production is regulated by many …

Background: Patients who smoke are at increased risk for chronic periodontitis (CP). Most
studies suggest that the microbial flora in these patients is similar to that found in non …

Bradykinin (BK), a pluripotent nonameric peptide, is known for its proinflammatory functions
in both tissue injury and allergic inflammation of the airway mucosa and submucosa. To …