[HTML][HTML] Molecular pathology of lung cancer: key to personalized medicine

L Cheng, RE Alexander, GT MacLennan… - Modern Pathology, 2012 - Elsevier
The majority of lung adenocarcinoma patients with epidermal growth factor receptor-(EGFR)
mutated or EML4–ALK rearrangement-positive tumors are sensitive to tyrosine kinase …

Clinical implications of the ErbB/epidermal growth factor (EGF) receptor family and its ligands in ovarian cancer

JM Lafky, JA Wilken, AT Baron, NJ Maihle - Biochimica et Biophysica Acta …, 2008 - Elsevier
The ERBB or EGF receptor (EGFR) proto-oncogene family, which consists of four structurally-
related transmembrane receptors (ie, EGFR, ErbB2, ErbB3, and ErbB4), plays an etiological …

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

G Bollée, M Flamant, S Schordan, C Fligny… - Nature medicine, 2011 - nature.com
Rapidly progressive glomerulonephritis (RPGN) is a life-threatening clinical syndrome and a
morphological manifestation of severe glomerular injury that is marked by a proliferative …

The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis

AC Dreux, DJ Lamb, H Modjtahedi, GAA Ferns - Atherosclerosis, 2006 - Elsevier
The epidermal growth factor receptor is a member of type-I growth factor receptor family with
tyrosine kinase activity that is activated following the binding of multiple cognate ligands …

Characterization of a spontaneously immortalized cell line (IOBA-NHC) from normal human conjunctiva

Y Diebold, M Calonge… - … & visual science, 2003 - iovs.arvojournals.org
purpose. To characterize a new nontransfected, spontaneously immortalized epithelial cell
line from normal human conjunctiva (IOBA-NHC), both morphologically and functionally, to …

An iPSC-derived exosome-pulsed dendritic cell vaccine boosts antitumor immunity in melanoma

R Wang, T Zhu, B Hou, X Huang - Molecular Therapy, 2023 - cell.com
Induced pluripotent stem cells (iPSCs) express a broad spectrum of tumor-associated
antigens and exert prophylactic effects on various tumors. However, some problems remain …

Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells

KA Adamczyk, S Klein-Scory, MM Tehrani, U Warnken… - Life sciences, 2011 - Elsevier
AIMS: Members of the epidermal growth factor receptor (EGFR) family represent validated
targets for anti-cancer therapy and EGFR inhibitors have also shown efficacy in pancreatic …

Alternative RNA splicing and cancer

S Liu, C Cheng - Wiley Interdisciplinary Reviews: RNA, 2013 - Wiley Online Library
Alternative splicing of pre‐messenger RNA (mRNA) is a fundamental mechanism by which a
gene can give rise to multiple distinct mRNA transcripts, yielding protein isoforms with …

Characterization of glycosylation sites of the epidermal growth factor receptor

Y Zhen, RM Caprioli, JV Staros - Biochemistry, 2003 - ACS Publications
The epidermal growth factor receptor is a transmembrane glycoprotein that mediates the
cellular responses to epidermal growth factor (EGF) and transforming growth factor-α (TGF …

The Epidermal Growth Factor Receptor Is a Relevant Host Factor in the Early Stages of The Zika Virus Life Cycle In Vitro

C Sabino, D Bender, ML Herrlein, E Hildt - Journal of virology, 2021 - Am Soc Microbiol
Zika virus (ZIKV) is a flavivirus that is well known for the epidemic in the Americas in 2015
and 2016 in which microcephaly in newborns and other neurological complications were …