In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Pseudomonas aeruginosa is a key pathogen of chronic infections in the lungs of cystic
fibrosis patients and in patients suffering from chronic wounds of diverse etiology. In these …

Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes
mortality in humans mainly due to respiratory infections caused by Pseudomonas …

Biofilm infections are one of the modern medical world's greatest challenges. Probably, all
non‐obligate intracellular bacteria and fungi can establish biofilms. In addition, there are …

Persistent neutrophil-dominated lung inflammation contributes to lung damage in cystic
fibrosis (CF). However, the mechanisms that drive persistent lung neutrophilia and tissue …

Despite the addition of cystic fibrosis transmembrane conductance regulator (CFTR)
modulators to the cystic fibrosis (CF) treatment regimen, patients with CF continue to suffer …

Rationale: Cystic fibrosis (CF) is caused by mutations in the CFTR (CF transmembrane
conductance regulator) gene and is characterized by sustained inflammation. ATP triggers …

Macrophage dysfunction has been well-described in Cystic Fibrosis (CF) and may contribute
to bacterial persistence in the lung. Whether CF macrophage dysfunction is related directly …

Highly-effective cystic fibrosis transmembrane conductance regulator (CFTR) modulator
therapy (HEMT) corrects the underlying molecular defect causing cystic fibrosis (CF) …

Cystic fibrosis (CF) is one of the most common life-limiting recessive genetic disorders in
Caucasians, caused by mutations in the cystic fibrosis transmembrane conductance …