[HTML][HTML] Alzheimer's disease: Insights and new prospects in disease pathophysiology, biomarkers and disease-modifying drugs

AR Monteiro, DJ Barbosa, F Remião, R Silva - Biochemical Pharmacology, 2023 - Elsevier
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases that
affect millions of people worldwide, with both prevalence and incidence increasing with age …

MicroRNAs as potential orchestrators of Alzheimer's disease-related pathologies: insights on current status and future possibilities

NZ Abuelezz, FE Nasr, MA AbdulKader… - Frontiers in Aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive and deleterious neurodegenerative disease,
strongly affecting the cognitive functions and memory of seniors worldwide. Around 58% of …

MicroRNAs and MAPKs: evidence of these molecular interactions in Alzheimer's disease

I Raffaele, S Silvestro, E Mazzon - International journal of molecular …, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder known to be the leading cause of
dementia worldwide. Many microRNAs (miRNAs) were found deregulated in the brain or …

Focus on the complex interconnection between cancer, narcolepsy and other neurodegenerative diseases: a possible case of orexin-dependent inverse comorbidity

MP Mogavero, A Silvani, LM DelRosso, M Salemi… - Cancers, 2021 - mdpi.com
Simple Summary This narrative review first describes from several points of view the
complex interrelationship between cancer and neurodegeneration, with special attention to …

The Role of miR-128 in Neurodegenerative Diseases

M Lanza, S Cuzzocrea, S Oddo, E Esposito… - International journal of …, 2023 - mdpi.com
Several neurodegenerative disorders are characterized by the accumulation of misfolded
proteins and are collectively known as proteinopathies. Alzheimer's disease (AD) …

MicroRNA-target interaction regulatory network in Alzheimer's disease

A Turk, T Kunej, B Peterlin - Journal of personalized medicine, 2021 - mdpi.com
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder and the most
common cause of dementia; however, early diagnosis of the disease is challenging …

Self-and partner-reported subjective memory complaints: association with objective cognitive impairment and risk of decline

L Zuroff, LEM Wisse, T Glenn, SX Xie… - Journal of …, 2022 - content.iospress.com
Background: Episodic memory decline is a hallmark of Alzheimer's disease (AD). Subjective
memory complaints (SMCs) may represent one of the earliest signs of impending cognitive …

Exploring the impact of miR-128 in inflammatory diseases: A comprehensive study on autoimmune diseases

R Margiana, HH Kzar, F Hussam, NM Hameed… - … -Research and Practice, 2023 - Elsevier
Abstract microRNAs (miRNAs) play a crucial role in various biological processes, including
immune system regulation, such as cell proliferation, tolerance (central and peripheral), and …

Chromatin Remodeling Factor SMARCA5 is Essential for Hippocampal Memory Maintenance via Metabolic Pathways in Mice

Y Qu, N Zhou, X Zhang, Y Li, XF Xu - Neuroscience Bulletin, 2023 - Springer
Gene transcription and new protein synthesis regulated by epigenetics play integral roles in
the formation of new memories. However, as an important part of epigenetics, the function of …

miR-128 as a Regulator of Synaptic Properties in 5xFAD Mice Hippocampal Neurons

I Shvarts-Serebro, A Sheinin, I Gottfried, L Adler… - Journal of Molecular …, 2021 - Springer
Alzheimer's disease (AD) is characterized by progressive synaptic dysfunction, deterioration
of neuronal transmission, and consequently neuronal death. Although there is no treatment …