Meiosis: dances between homologs

D Zickler, N Kleckner - Annual Review of Genetics, 2023 - annualreviews.org
The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …

Meiotic recombination: the essence of heredity

N Hunter - Cold Spring Harbor perspectives in biology, 2015 - cshperspectives.cshlp.org
The study of homologous recombination has its historical roots in meiosis. In this context,
recombination occurs as a programmed event that culminates in the formation of crossovers …

Recombination, pairing, and synapsis of homologs during meiosis

D Zickler, N Kleckner - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
Recombination is a prominent feature of meiosis in which it plays an important role in
increasing genetic diversity during inheritance. Additionally, in most organisms …

Repair of strand breaks by homologous recombination

M Jasin, R Rothstein - Cold Spring Harbor perspectives …, 2013 - cshperspectives.cshlp.org
In this review, we discuss the repair of DNA double-strand breaks (DSBs) using a
homologous DNA sequence (ie, homologous recombination [HR]), focusing mainly on yeast …

The molecular biology of meiosis in plants

R Mercier, C Mézard, E Jenczewski… - Annual review of …, 2015 - annualreviews.org
Meiosis is the cell division that reshuffles genetic information between generations.
Recently, much progress has been made in understanding this process; in particular, the …

Mechanisms and Regulation of Mitotic Recombination in Saccharomyces cerevisiae

LS Symington, R Rothstein, M Lisby - Genetics, 2014 - academic.oup.com
Homology-dependent exchange of genetic information between DNA molecules has a
profound impact on the maintenance of genome integrity by facilitating error-free DNA …

Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions

K Choi, X Zhao, AJ Tock, C Lambing… - Genome …, 2018 - genome.cshlp.org
Meiotic recombination initiates from DNA double-strand breaks (DSBs) generated by SPO11
topoisomerase-like complexes. Meiotic DSB frequency varies extensively along eukaryotic …

Septin-Mediated Plant Cell Invasion by the Rice Blast Fungus, Magnaporthe oryzae

YF Dagdas, K Yoshino, G Dagdas, LS Ryder, E Bielska… - Science, 2012 - science.org
To cause rice blast disease, the fungus Magnaporthe oryzae develops a pressurized dome-
shaped cell called an appressorium, which physically ruptures the leaf cuticle to gain entry …

Holliday junction resolvases

HDM Wyatt, SC West - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
Four-way DNA intermediates, called Holliday junctions (HJs), can form during meiotic and
mitotic recombination, and their removal is crucial for chromosome segregation. A group of …

FANCM limits meiotic crossovers

W Crismani, C Girard, N Froger, M Pradillo, JL Santos… - Science, 2012 - science.org
The number of meiotic crossovers (COs) is tightly regulated within a narrow range, despite a
large excess of molecular precursors. The factors that limit COs remain largely unknown …