An evolving new paradigm: endothelial cells–conditional innate immune cells
Endothelial cells (ECs) are a heterogeneous population that fulfills many physiological
processes. ECs also actively participate in both innate and adaptive immune responses …
processes. ECs also actively participate in both innate and adaptive immune responses …
Chemokines in cutaneous wound healing
R Gillitzer, M Goebeler - Journal of leukocyte biology, 2001 - academic.oup.com
Healing of wounds is one of the most complex biological events afterbirth as a result of the
interplay of different tissue structures and alarge number of resident and infiltrating cell …
interplay of different tissue structures and alarge number of resident and infiltrating cell …
IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis
A Li, S Dubey, ML Varney, BJ Dave… - The Journal of …, 2003 - journals.aai.org
IL-8, a member of the chemokine family, has been shown to play an important role in tumor
growth, angiogenesis, and metastasis. The objective of this study was to determine the …
growth, angiogenesis, and metastasis. The objective of this study was to determine the …
The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
DJ Brat, AC Bellail, EG Van Meir - Neuro-oncology, 2005 - academic.oup.com
Abstract Interleukin-8 (IL-8, or CXCL8), which is a chemokine with a defining CXC amino
acid motif that was initially characterized for its leukocyte chemotactic activity, is now known …
acid motif that was initially characterized for its leukocyte chemotactic activity, is now known …
Chemokines in health and disease
D Raman, T Sobolik-Delmaire, A Richmond - Experimental cell research, 2011 - Elsevier
Chemokines and their receptors play a key role in development and homeostasis as well as
in the pathogenesis of tumors and autoimmune diseases. Chemokines are involved in the …
in the pathogenesis of tumors and autoimmune diseases. Chemokines are involved in the …
Chemokine receptors and their role in inflammation and infectious diseases
Chemokines are small peptides that are potent activators and chemoattractants for leukocyte
subpopulations and some nonhemopoietic cells. Their actions are mediated by a family of 7 …
subpopulations and some nonhemopoietic cells. Their actions are mediated by a family of 7 …
[HTML][HTML] Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and …
C Wetzler, H Kämpfer, B Stallmeyer… - Journal of investigative …, 2000 - Elsevier
Chemokines are seen as the stimuli that largely control leukocyte migration. To assess
whether the severely impaired process of cutaneous repair observed in genetically diabetic …
whether the severely impaired process of cutaneous repair observed in genetically diabetic …
[HTML][HTML] Lipopolysaccharide signaling in endothelial cells
SM Dauphinee, A Karsan - Laboratory investigation, 2006 - Elsevier
Sepsis is the systemic immune response to severe bacterial infection. The innate immune
recognition of bacterial and viral products is mediated by a family of transmembrane …
recognition of bacterial and viral products is mediated by a family of transmembrane …
Transiently entrapped circulating tumor cells interact with neutrophils to facilitate lung metastasis development
It is unknown why only a minority of circulating tumor cells trapped in lung capillaries form
metastases and involvement of immune cells remains uncertain. A novel model has been …
metastases and involvement of immune cells remains uncertain. A novel model has been …
The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8
JE De Larco, BRK Wuertz, LT Furcht - Clinical Cancer Research, 2004 - AACR
In the last decade, several groups have shown a direct correlation between the
inappropriate or ectopic release of interleukin (IL)-8 by tumor cells in vitro and their growth …
inappropriate or ectopic release of interleukin (IL)-8 by tumor cells in vitro and their growth …