IL-25, also known as IL-17E, is a unique cytokine of the IL-17 family. Indeed, IL-25
exclusively was shown to strongly induce expression of the cytokines associated with type 2 …

Psoriasis is a common chronic inflammatory skin disease, associated with substantial
comorbidity. TH17 lymphocytes, differentiating under the influence of dendritic cell-derived …

Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …

Psoriasis is a chronic inflammatory skin condition associated with immune dysregulation.
The immunologic cascade mediated by the interleukin (IL)-17 pathway plays a critically …

Interleukin-17 (IL-17) family cytokines are potent drivers of inflammatory responses.
Although IL-17 was originally identified as a cytokine that induces protective effects against …

Considering the role of epidermal keratinocytes, they occupy more than 90% of the
epidermis, form a physical barrier, and also function as innate immune barrier. For example …

Skin acts as the primary interface between the body and the environment. The skin immune
system is composed of a complex network of immune cells and factors that provide the first …

Summary Background The interleukin (IL)‐23/IL‐17 immune axis is of central importance in
psoriasis. However, the impact of IL‐17 family cytokines other than IL‐17A in psoriasis has …

Abstract Interleukin-25 (IL-25), also known as IL-17E, is a cytokine belonging to the IL-17
family. IL-25 is abundantly expressed by Th2 cells and various kinds of epithelial cells. IL-25 …