Chronic liver diseases such as nonalcoholic fatty liver disease (NAFLD) or viral hepatitis are
characterized by persistent inflammation and subsequent liver fibrosis. Liver fibrosis critically …

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease and is
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …

Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …

The progression of chronic liver diseases (CLD), irrespective of etiology, involves chronic
parenchymal injury, persistent activation of inflammatory response as well as sustained …

Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous group of liver diseases
characterized by the accumulation of fat in the liver. The heterogeneity of NAFLD is reflected …

Hepatic fibrosis is a dynamic process characterized by the net accumulation of extracellular
matrix resulting from chronic liver injury of any aetiology, including viral infection, alcoholic …

Progressive liver fibrosis, induced by chronic viral and metabolic disorders, leads to more
than one million deaths annually via development of cirrhosis, although no antifibrotic …

In the past decade, nonalcoholic fatty liver disease (NAFLD) has become a leading cause of
chronic liver disease and cirrhosis, as well as an important risk factor for hepatocellular …

Background and Aims Nonalcoholic steatohepatitis is rapidly becoming the leading cause of
liver failure and indication for liver transplantation. Hepatic inflammation is a key feature of …

Liver fibrosis, as an excess deposition of extracellular matrix (ECM) components, results
from chronic liver injury as well as persistent activation of inflammatory response and of …