Breakthroughs in hepatitis C research: from discovery to cure

MP Manns, B Maasoumy - Nature reviews Gastroenterology & …, 2022 - nature.com
In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

Potential interventions for novel coronavirus in China: A systematic review

L Zhang, Y Liu - Journal of medical virology, 2020 - Wiley Online Library
An outbreak of a novel coronavirus (COVID‐19 or 2019‐CoV) infection has posed significant
threats to international health and the economy. In the absence of treatment for this virus …

Anti-HCV, nucleotide inhibitors, repurposing against COVID-19

AA Elfiky - Life sciences, 2020 - Elsevier
Aims A newly emerged Human Coronavirus (HCoV) is reported two months ago in Wuhan,
China (COVID-19). Until today> 2700 deaths from the 80,000 confirmed cases reported …

EASL recommendations on treatment of hepatitis C: final update of the series☆

JM Pawlotsky, F Negro, A Aghemo, M Berenguer… - Journal of …, 2020 - Elsevier
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …

Novel coronavirus treatment with ribavirin: groundwork for an evaluation concerning COVID‐19

JS Khalili, H Zhu, NSA Mak, Y Yan… - Journal of medical …, 2020 - Wiley Online Library
Confronting the challenge of the outbreak of COVID‐19 should sharpen our focus on global
drug access as a key issue in antiviral therapy testing. The testing and adoption of effective …

Shared and distinct functions of type I and type III interferons

HM Lazear, JW Schoggins, MS Diamond - Immunity, 2019 - cell.com
Type I interferons (IFNs)(IFN-α, IFN-β) and type III IFNs (IFN-λ) share many properties,
including induction by viral infection, activation of shared signaling pathways, and …

EASL recommendations on treatment of hepatitis C 2016

European Association for The Study of The Liver - Journal of hepatology, 2017 - Elsevier
Hepatitis C virus (HCV) infection is one of the main causes of chronic liver disease
worldwide [1]. The long-term impact of HCV infection is highly variable, ranging from minimal …

Hepatitis C virus infection

MP Manns, M Buti, ED Gane, JM Pawlotsky… - Nature reviews Disease …, 2017 - nature.com
Hepatitis C virus (HCV) is a hepatotropic RNA virus that causes progressive liver damage,
which might result in liver cirrhosis and hepatocellular carcinoma. Globally, between 64 and …

EASL recommendations on treatment of hepatitis C 2018

JM Pawlotsky, F Negro, A Aghemo, M Berenguer… - Journal of …, 2018 - Elsevier
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …

Scaling up prevention and treatment towards the elimination of hepatitis C: a global mathematical model

A Heffernan, GS Cooke, S Nayagam, M Thursz… - The Lancet, 2019 - thelancet.com
Background The revolution in hepatitis C virus (HCV) treatment through the development of
direct-acting antivirals (DAAs) has generated international interest in the global elimination …