Fate of microglia during HIV‐1 infection: From activation to senescence?
NC Chen, AT Partridge, C Sell, C Torres… - Glia, 2017 - Wiley Online Library
Microglia support productive human immunodeficiency virus type 1 (HIV‐1) infection and
disturbed microglial function could contribute to the development of HIV‐associated …
disturbed microglial function could contribute to the development of HIV‐associated …
Drug induced mitochondrial dysfunction: Mechanisms and adverse clinical consequences
M Vuda, A Kamath - Mitochondrion, 2016 - Elsevier
Several commonly used medications impair mitochondrial function resulting in adverse
effects or toxicities. Drug induced mitochondrial dysfunction may be a consequence of …
effects or toxicities. Drug induced mitochondrial dysfunction may be a consequence of …
Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells
M Spinazzi, A Casarin, V Pertegato, L Salviati… - Nature protocols, 2012 - nature.com
The assessment of mitochondrial respiratory chain (RC) enzymatic activities is essential for
investigating mitochondrial function in several situations, including mitochondrial disorders …
investigating mitochondrial function in several situations, including mitochondrial disorders …
[HTML][HTML] Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health
Blood based bioenergetic profiling strategies are emerging as potential reporters of systemic
mitochondrial function; however, the extent to which these measures reflect the bioenergetic …
mitochondrial function; however, the extent to which these measures reflect the bioenergetic …
Mitochondrial effects of HIV infection on the peripheral blood mononuclear cells of HIV-infected patients who were never treated with antiretrovirals
To investigate the effects of HIV infection on mitochondrial DNA (mtDNA) content and other
mitochondrial parameters, we used peripheral blood mononuclear cells (PBMCs) from 25 …
mitochondrial parameters, we used peripheral blood mononuclear cells (PBMCs) from 25 …
Reversible inhibition of mitochondrial protein synthesis during linezolid-related hyperlactatemia
The objective of the present study was to determine the mitochondrial toxicity mechanisms of
linezolid-related hyperlactatemia. Five patients on a long-term schedule of linezolid …
linezolid-related hyperlactatemia. Five patients on a long-term schedule of linezolid …
Increased oxidative stress is correlated with mitochondrial dysfunction in chagasic patients
J Wen, PC Yachelini, A Sembaj, RE Manzur… - Free Radical Biology and …, 2006 - Elsevier
Previously, we have shown in an experimental model of Trypanosoma cruzi infection that
increased oxidative stress and antioxidant insufficiency are associated with myocardial …
increased oxidative stress and antioxidant insufficiency are associated with myocardial …
The footprints of mitochondrial impairment and cellular energy crisis in the pathogenesis of xenobiotics-induced nephrotoxicity, serum electrolytes imbalance, and …
R Heidari - Toxicology, 2019 - Elsevier
Fanconi's Syndrome (FS) is a disorder characterized by impaired renal proximal tubule
function. FS is associated with a vast defect in the renal reabsorption of several chemicals …
function. FS is associated with a vast defect in the renal reabsorption of several chemicals …
Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine
G Song, E Napoli, S Wong, R Hagerman, S Liu… - Molecular …, 2016 - Springer
A 55–200 expansion of the CGG nucleotide repeat in the 5′-UTR of the fragile X mental
retardation 1 gene (FMR1) is the hallmark of the triplet nucleotide disease known as the …
retardation 1 gene (FMR1) is the hallmark of the triplet nucleotide disease known as the …
Mitochondria as oxidative signaling organelles in T-cell activation: physiological role and pathological implications
MM Kamiński, D Röth, PH Krammer… - Archivum immunologiae et …, 2013 - Springer
Early scientific reports limited the cell biological role of reactive oxygen species (ROS) to the
cause of pathological damage. However, extensive research performed over the last decade …
cause of pathological damage. However, extensive research performed over the last decade …