Microglia support productive human immunodeficiency virus type 1 (HIV‐1) infection and
disturbed microglial function could contribute to the development of HIV‐associated …

Several commonly used medications impair mitochondrial function resulting in adverse
effects or toxicities. Drug induced mitochondrial dysfunction may be a consequence of …

The assessment of mitochondrial respiratory chain (RC) enzymatic activities is essential for
investigating mitochondrial function in several situations, including mitochondrial disorders …

Blood based bioenergetic profiling strategies are emerging as potential reporters of systemic
mitochondrial function; however, the extent to which these measures reflect the bioenergetic …

To investigate the effects of HIV infection on mitochondrial DNA (mtDNA) content and other
mitochondrial parameters, we used peripheral blood mononuclear cells (PBMCs) from 25 …

The objective of the present study was to determine the mitochondrial toxicity mechanisms of
linezolid-related hyperlactatemia. Five patients on a long-term schedule of linezolid …

Previously, we have shown in an experimental model of Trypanosoma cruzi infection that
increased oxidative stress and antioxidant insufficiency are associated with myocardial …

Fanconi's Syndrome (FS) is a disorder characterized by impaired renal proximal tubule
function. FS is associated with a vast defect in the renal reabsorption of several chemicals …

A 55–200 expansion of the CGG nucleotide repeat in the 5′-UTR of the fragile X mental
retardation 1 gene (FMR1) is the hallmark of the triplet nucleotide disease known as the …

Early scientific reports limited the cell biological role of reactive oxygen species (ROS) to the
cause of pathological damage. However, extensive research performed over the last decade …