[HTML][HTML] New drugs are not enough‑drug repositioning in oncology: An update
RG Armando… - … Journal of Oncology, 2020 - spandidos-publications.com
Drug repositioning refers to the concept of discovering novel clinical benefits of drugs that
are already known for use treating other diseases. The advantages of this are that several …
are already known for use treating other diseases. The advantages of this are that several …
Drug repurposing: An emerging strategy in alleviating skin cancer
P Kumbhar, K Kole, T Yadav, A Bhavar… - European Journal of …, 2022 - Elsevier
Skin cancer is one of the most common forms of cancer. Several million people are
estimated to have affected with this condition worldwide. Skin cancer generally includes …
estimated to have affected with this condition worldwide. Skin cancer generally includes …
[图书][B] Profiles of drug substances, excipients, and related methodology
HG Brittain - 2020 - books.google.com
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 45, presents
comprehensive reviews of drug substances and additional materials, with critical review …
comprehensive reviews of drug substances and additional materials, with critical review …
Macroporous scaffold surface modified with biological macromolecules and piroxicam-loaded gelatin nanofibers toward meniscus cartilage repair
Meniscus cartilage has poor self-healing capacity in the inner zone and its damage leads to
articular cartilage degeneration. Here we have developed hybrid constructs using …
articular cartilage degeneration. Here we have developed hybrid constructs using …
Box-Behnken design optimization and in vitro cell based evaluation of piroxicam loaded core-shell type hybrid nanocarriers for prostate cancer
CT Sengel-Turk, E Ozkan, F Bakar-Ates - Journal of Pharmaceutical and …, 2022 - Elsevier
In the present research, piroxicam entrapped core-shell lipid-polymer hybrid nanocarriers
were developed and also evaluated in terms of nanoparticle features and cell-based in vitro …
were developed and also evaluated in terms of nanoparticle features and cell-based in vitro …
[HTML][HTML] L-arginine/nitric oxide pathway is altered in colorectal cancer and can be modulated by novel derivatives from oxicam class of non-steroidal anti-inflammatory …
M Krzystek-Korpacka, B Szczęśniak-Sięga, I Szczuka… - Cancers, 2020 - mdpi.com
Simple Summary Nitric oxide and arginine metabolism in colorectal cancer (CRC) holds
potential for therapeutic intervention. We hypothesized that it can be modulated by oxicams …
potential for therapeutic intervention. We hypothesized that it can be modulated by oxicams …
[HTML][HTML] Repurposing of drug candidates for treatment of skin cancer
H Cortes, OD Reyes-Hernandez, S Alcala-Alcala… - Frontiers in …, 2021 - frontiersin.org
Skin cancers are highly prevalent malignancies that affect millions of people worldwide.
These include melanomas and nonmelanoma skin cancers. Melanomas are among the …
These include melanomas and nonmelanoma skin cancers. Melanomas are among the …
Identifying alkaline phosphatase inhibitory potential of cyclooxygenase-2 inhibitors: Insights from molecular docking, MD simulations, molecular expression analysis in …
Abstract Alkaline phosphatases (APs, EC 3.1. 3.1) belong to a superfamily of biological
macromolecules that dephosphorylate many phosphometabolites and phosphoproteins and …
macromolecules that dephosphorylate many phosphometabolites and phosphoproteins and …
[HTML][HTML] Mixed-generation PAMAM G3-G0 megamer as a drug delivery system for nimesulide: Antitumor activity of the conjugate against human squamous carcinoma …
M Zaręba, P Sareło, M Kopaczyńska… - International journal of …, 2019 - mdpi.com
Polyhydroxylated dendrimer was synthesized from poly (amidoamine)(PAMAM) dendrimer
generation 3 by addition of glycidol (G3gl). G3gl megamer was further modified by binding …
generation 3 by addition of glycidol (G3gl). G3gl megamer was further modified by binding …
Synthesis, characterization, molecular modeling studies, and biological evaluation of metal piroxicam complexes (M= Ni (II), Pt (IV), Pd (II), Ag (I)) as antibacterial and …
AM Soliman, AMK El‐sagheir… - Drug Development …, 2024 - Wiley Online Library
Four piroxicam metal complexes; NiL2, PtL2, PdL2, and AgL were synthesized and
characterized by different techniques with enhanced antibacterial and anticancer activity …
characterized by different techniques with enhanced antibacterial and anticancer activity …