An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

Background Childhood maltreatment is the most important preventable cause of
psychopathology accounting for about 45% of the population attributable risk for childhood …

Objective: Black Americans in the United States are disproportionately exposed to childhood
adversity compared with White Americans. Such disparities may contribute to race-related …

A growing body of research has examined the impact of childhood adversity on neural
structure and function. Advances in our understanding of the neurodevelopmental …

Children exposed to various forms of adversity early in life are at increased risk for a broad
range of developmental difficulties, affecting both cognitive and emotional adjustment. We …

Over the past decade, a growing area of research has focused on adverse childhood
experiences (ACEs) and their impacts on neural and developmental outcomes. Work in the …

BackgroundChildhood early life stress (ELS) increases risk of adulthood major depressive
disorder (MDD) and is associated with altered brain structure and function. It is unclear …

Environmental challenges are part of daily life for any individual. In fact, stress appears to be
increasingly present in our modern, and demanding, industrialized society. Virtually every …

Early life stress–including experience of child maltreatment, neglect, separation from or loss
of a parent, and other forms of adversity–increases lifetime risk of mood, anxiety, and …

An update to the classic text that links neuroscience and human behavior in the context of
therapy. This groundbreaking book explores the recent revolution in psychotherapy that has …