Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI-MSI) in Disease Diagnosis: An Overview.

BS Kumar - Analytical Methods, 2023 - pubs.rsc.org
Tissue analysis, which is essential to histology and is considered the benchmark for the
diagnosis and prognosis of many illnesses, including cancer, is significant. During surgery …

[HTML][HTML] The past, present and future of flow cytometry in central nervous system malignancies

E Vartholomatos, G Vartholomatos, GA Alexiou… - Methods and …, 2021 - mdpi.com
Central nervous system malignancies (CNSMs) are categorized among the most aggressive
and deadly types of cancer. The low median survival in patients with CNSMs is partly …

Mass spectrometry imaging as a tool for surgical decision‐making

D Calligaris, I Norton, DR Feldman… - Journal of Mass …, 2013 - Wiley Online Library
Despite significant advances in image‐guided therapy, surgeons are still too often left with
uncertainty when deciding to remove tissue. This binary decision between removing and …

Development concepts of a smart cyber operating theater (SCOT) using ORiN technology

J Okamoto, K Masamune, H Iseki… - Biomedical Engineering …, 2018 - degruyter.com
Currently, networking has not progressed in the treatment room. Almost every medical
device in the treatment room operates as a stand-alone device. In this project, we aim to …

Role of neurochemical navigation with 5-aminolevulinic acid during intraoperative MRI-guided resection of intracranial malignant gliomas

S Yamada, Y Muragaki, T Maruyama, T Komori… - Clinical neurology and …, 2015 - Elsevier
Objective To evaluate the role of the neurochemical navigation with 5-aminolevulinic acid (5-
ALA) during intraoperative MRI (iMRI)-guided resection of the intracranial malignant …

Rapid assessment of resection margins during breast conserving surgery using intraoperative flow cytometry

G Vartholomatos, H Harissis, M Andreou, V Tatsi… - Clinical Breast …, 2021 - Elsevier
Background Positive margins are the most important factor for recurrence of the disease
after breast-conserving surgery. Several methods have been developed throughout the …

Novel intraoperative strategies for enhancing tumor control: Future directions

AF Haddad, MK Aghi, N Butowski - Neuro-oncology, 2022 - academic.oup.com
Maximal safe surgical resection plays a key role in the care of patients with gliomas. A range
of technologies have been developed to aid surgeons in distinguishing tumor from normal …

[HTML][HTML] Assessment of gliomas' grade of malignancy and extent of resection using intraoperative flow cytometry

G Vartholomatos, GS Markopoulos, E Vartholomatos… - Cancers, 2023 - mdpi.com
Simple Summary Intraoperative Flow Cytometry (iFC) is a new technique that can help
assess the malignancy grade, diagnose tumor type, and evaluate resection margins during …

Intraoperative flow cytometry for head and neck lesions. Assessment of malignancy and tumour-free resection margins

G Vartholomatos, L Basiari, G Exarchakos… - Oral Oncology, 2019 - Elsevier
Head and neck cancer poses a significant health problem worldwide. We set out to
investigate the value of rapid intraoperative cell cycle analysis by flow cytometry for the …

Ambient ionization mass spectrometry imaging for disease diagnosis: Excitements and challenges

S Banerjee - Journal of biosciences, 2018 - Springer
Tissue analysis in histology is extremely important and also considered to be a gold
standard to diagnose and prognosticate several diseases including cancer. Intraoperative …