Monoclonal antibodies (mAbs) are the fastest-growing biological therapeutics with important
applications ranging from cancers, autoimmunity diseases and metabolic disorders to …

Cell‐surface interactions play a crucial role for biomaterial application in orthopaedics. It is
evident that not only the chemical composition of solid substances influence cellular …

Understanding external factors that determine cellular phenotypic responses is of key
interest in the field of biomaterials. Currently, material surface characteristics, protein …

The EF-hand superfamily of calcium binding proteins includes the S100, calcium binding
protein, and troponin subfamilies. This study represents a genome, structure, and …

In this paper we discuss the possibility of a general paradigm for cell–biomaterial and cell–
nanoparticle interactions. The basis of the paradigm is that the nature of the biomaterial or …

The phenomena of protein reconstitution and three‐dimensional domain swapping reveal
that highly similar structures can be obtained whether a protein is comprised of one or more …

Protein stabilization was achieved through in vivo screening based on the thermodynamic
linkage between protein folding and fragment complementation. The split GFP system was …

Autocatalytic cleavage of lithostathine leads to the formation of quadruple-helical fibrils (QHF-
litho) that are present in Alzheimer's disease. Here we show that such fibrils also occur in …

Abstract Domain swapping is the process by which identical proteins exchange reciprocal
segments to generate dimers. Here we introduce induced domain swapping (INDOS) as a …

ABSTRACT A highly N-phosphonomethylglycine (glyphosate)-resistant Pseudomonas
fluorescens G2 5-enolpyruvyl shikimate-3-phosphate synthase (EPSPS) was mapped to …