Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …
attention in both basic and translational biomedical studies. Although the classical hydrogels …
Metalloproteinases and their inhibitors: potential for the development of new therapeutics
M Raeeszadeh-Sarmazdeh, LD Do, BG Hritz - Cells, 2020 - mdpi.com
The metalloproteinase (MP) family of zinc-dependent proteases, including matrix
metalloproteinases (MMPs), a disintegrin and metalloproteases (ADAMs), and a disintegrin …
metalloproteinases (MMPs), a disintegrin and metalloproteases (ADAMs), and a disintegrin …
Treatment with mesenchymal stem cell‐derived nanovesicle‐containing gelatin methacryloyl hydrogels alleviates osteoarthritis by modulating chondrogenesis and …
L Pang, H Jin, Z Lu, F Xie, H Shen, X Li… - Advanced …, 2023 - Wiley Online Library
Osteoarthritis is a degenerative disorder that can severely affect joints, and new treatment
strategies are urgently needed. Administration of mesenchymal stem cell (MSC)‐derived …
strategies are urgently needed. Administration of mesenchymal stem cell (MSC)‐derived …
[HTML][HTML] Smart dental materials for antimicrobial applications
Smart biomaterials can sense and react to physiological or external environmental stimuli
(eg, mechanical, chemical, electrical, or magnetic signals). The last decades have seen …
(eg, mechanical, chemical, electrical, or magnetic signals). The last decades have seen …
Hybrid gelatin hydrogels in nanomedicine applications
Gelatin based hydrogels are often incorporated with supporting materials such as chitosan,
poly (vinyl alcohol), alginate, carbon nanotubes, and hyaluronic acid. These hybrid materials …
poly (vinyl alcohol), alginate, carbon nanotubes, and hyaluronic acid. These hybrid materials …
Highly tunable bioactive fiber-reinforced hydrogel for guided bone regeneration
One of the most damaging pathologies that affects the health of both soft and hard tissues
around the tooth is periodontitis. Clinically, periodontal tissue destruction has been …
around the tooth is periodontitis. Clinically, periodontal tissue destruction has been …
Biotin–Avidin System-Based Delivery Enhances the Therapeutic Performance of MSC-Derived Exosomes
D Deng, X Li, JJ Zhang, Y Yin, Y Tian, D Gan, R Wu… - ACS …, 2023 - ACS Publications
Exosomes (EXs) shed by mesenchymal stem cells (MSCs) are potent therapeutic agents
that promote wound healing and regeneration, but when used alone in vivo, their …
that promote wound healing and regeneration, but when used alone in vivo, their …
A novel injectable piezoelectric hydrogel for periodontal disease treatment
Periodontal disease is a multifactorial, bacterially induced inflammatory condition
characterized by the progressive destruction of periodontal tissues. The successful …
characterized by the progressive destruction of periodontal tissues. The successful …
Injectable “nano-micron” combined gene-hydrogel microspheres for local treatment of osteoarthritis
B Li, F Wang, F Hu, T Ding, P Huang, X Xu, J Liang… - NPG Asia …, 2022 - nature.com
Sustained and controllable local gene therapy is a potential method for treating osteoarthritis
(OA) through the delivery of therapeutic microRNAs (miRNAs) to targeted cells. However …
(OA) through the delivery of therapeutic microRNAs (miRNAs) to targeted cells. However …
Gelatin methacryloyl hydrogel as an injectable scaffold with multi-therapeutic effects to promote antimicrobial disinfection and angiogenesis for regenerative …
N Dubey, JS Ribeiro, Z Zhang, J Xu… - Journal of Materials …, 2023 - pubs.rsc.org
Regenerative endodontics represents a paradigm shift in dental pulp therapy for necrotic
young permanent teeth. However, there are still challenges associated with attaining …
young permanent teeth. However, there are still challenges associated with attaining …