Objective Summarize the current evidence on efficacy and tolerability of vagus nerve
stimulation (VNS), responsive neurostimulation (RNS), and deep brain stimulation (DBS) …

Background: Epilepsy is a chronic brain disease that is caused by various factors and
characterized by recurrent, episodic and temporary central nervous system dysfunction …

Head-to-head comparison of treatment modalities such as VNS, DBS and RNS across
different epileptic syndromes are required to decide which treatment modality is the most …

Epilepsy is the fourth most common neurological disorder, but current treatment options
provide limited efficacy and carry the potential for problematic adverse effects. There is an …

Brain stimulation is increasingly used in epilepsy patients with insufficient therapeutic
response to pharmacological treatment. Whereas vagus nerve stimulation with implanted …

BACKGROUND: Organ ischemia-reperfusion injury often induces local and systemic
inflammatory responses, which in turn worsen organ injury. These inflammatory responses …

Key points On‐demand optogenetic inhibition of glutamatergic neurons in the fastigial
nucleus of the cerebellum does not alter hippocampal seizures in a mouse model of …

Objectives To compare the short-and long-term efficacies as well as tolerability of vagus
nerve stimulation (VNS) for the patients with drug-resistant epilepsy (DRE) in comparison …

Background Epilepsy surgery is an important treatment option for people with drug-resistant
epilepsy. Surgical procedures for epilepsy are underutilized worldwide, but it is far worse in …

Objective: Vagus nerve stimulation (VNS) has been used for adjunctive treatment in drug
resistant epilepsy (DRE) for decades. Nevertheless, information is lacking on possible …