The Covid-19 pandemic has introduced an array of organspecific and systemic phenotypes-
some previously observed in viral infections, including severe acute respiratory syndrome …

Host defense against infection is based on two crucial mechanisms: the inflammatory
response and the activation of coagulation. Platelets are involved in both hemostasis and …

Abstract Keywords: COVID-19; platelet count; severe; thrombocytopenia; meta-analysis EN
COVID-19 platelet count severe thrombocytopenia meta-analysis e29 e33 5 07/01/20 …

Platelets are small circulating anucleate cells that are of crucial importance in haemostasis.
Over the last decade, it has become increasingly clear that platelets play an important role in …

Platelets can be considered sentinels of vascular system due to their high number in the
circulation and to the range of functional immunoreceptors they express. Platelets express a …

Beyond haemostasis, platelets have emerged as versatile effectors of the immune response.
The contribution of platelets in inflammation, tissue integrity and defence against infections …

Background The epidemiology of thrombocytopenia in critically ill patients has not been well
characterized. The objective of this study was to systematically review the prevalence …

Thrombocytopenia is a common finding in sepsis and associated with a worse outcome. We
used a mouse model of pneumonia-derived sepsis caused by the human pathogen …

Background Thrombocytopenia is the most common hemostatic disorder in critically ill
patients. The objective of this study was to describe the incidence, risk factors, and outcomes …

Although it has long been known that patients with sepsis often have thrombocytopenia and
that septic patients with severe thrombocytopenia have a poor prognosis and higher …