Redefining autoimmune disorders' pathoetiology: implications for mood and psychotic disorders' association with neurodegenerative and classical autoimmune …

G Anderson, AF Almulla, RJ Reiter, M Maes - Cells, 2023 - mdpi.com
Although previously restricted to a limited number of medical conditions, there is a growing
appreciation that 'autoimmune'(or immune-mediated) processes are important aspects of a …

Crosstalk between aging, circadian rhythm, and melatonin

AK Verma, MI Khan, F Ashfaq, SI Rizvi - Rejuvenation Research, 2023 - liebertpub.com
Circadian rhythms (CRs) are 24-hour periodic oscillations governed by an endogenous
circadian pacemaker located in the suprachiasmatic nucleus (SCN), which organizes the …

Design, Synthesis, In Silico Studies and In Vitro Evaluation of New Indole-and/or Donepezil-like Hybrids as Multitarget-Directed Agents for Alzheimer's Disease

VT Angelova, B Georgiev, T Pencheva, I Pajeva… - Pharmaceuticals, 2023 - mdpi.com
Alzheimer's disease (AD) is considered a complex neurodegenerative condition which
warrants the development of multitargeted drugs to tackle the key pathogenetic mechanisms …

Melatonin as a chronobiotic/cytoprotective agent in REM sleep behavior disorder

DP Cardinali, A Garay - Brain Sciences, 2023 - mdpi.com
Dream-enactment behavior that emerges during episodes of rapid eye movement (REM)
sleep without muscle atonia is a parasomnia known as REM sleep behavior disorder (RBD) …

Combination Supplements for Endometrial Cancer

M Mondal, A Lahiri, H Vundavilli… - 2023 IEEE 23rd …, 2023 - ieeexplore.ieee.org
This paper suggests an optimal supplement combination (EGCG, Curcumin, Melatonin,
Aspirin, and Baicalein) for treating endometrial cancer using a Boolean model. Endometrial …