The search for novel anti-infectives is one of the most important challenges in natural
product research, as diseases caused by bacteria, viruses, and fungi are influencing the …

Many bacteria have evolved specialized nanomachines with the remarkable ability to inject
multiple bacterially encoded effector proteins into eukaryotic or prokaryotic cells. Known as …

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a
systematic analysis for the Glo Page 1 Global Health Metrics 1204 www.thelancet.com Vol 396 …

Electrocatalysis by atomic catalysts is a major focus of chemical and energy conversion
effort. Although transition-metal-based bulk electrocatalysts for electrochemical application …

Among the human health conditions linked to microbial communities, phenotypes are often
associated with only a subset of strains within causal microbial groups. Although it has been …

Invasive gastric carcinoma is preceded by a cascade of precancerous lesions. The first
recognized histologic change is active chronic inflammation, which may persist as such: non …

Gastric cancer is the third most common cause of cancer-related death in the world. It is now
well-established that Helicobacter pylori infection predispose individuals toward gastric …

Co-evolution between host and pathogen is, in principle, a powerful determinant of the
biology and genetics of infection and disease. Yet co-evolution has proven difficult to …

Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven
populations and subpopulations with distinct geographical distributions. These modern …

The Gram-negative bacterium Helicobacter pylori is a causative agent of gastritis and peptic
ulcer disease in humans. Strains producing the CagA antigen (cagA+) induce strong gastric …