Recent aspects of the effects of zinc on human health

CT Chasapis, PSA Ntoupa, CA Spiliopoulou… - Archives of …, 2020 - Springer
Zinc (Zn) is one of the most important essential nutrients of great public health significance. It
is involved in numerous biological functions and it is considered as a multipurpose trace …

[HTML][HTML] Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases

S Choi, X Liu, Z Pan - Acta Pharmacologica Sinica, 2018 - nature.com
Zinc is an essential nutrient for human health and has anti-oxidative stress and anti-
inflammatory functions. The association between zinc deficiency and the development of …

[HTML][HTML] Role of zinc homeostasis in the pathogenesis of diabetes and obesity

A Fukunaka, Y Fujitani - International journal of molecular sciences, 2018 - mdpi.com
Zinc deficiency is a risk factor for obesity and diabetes. However, until recently, the
underlying molecular mechanisms remained unclear. The breakthrough discovery that the …

[HTML][HTML] Nutrition in patients with type 2 diabetes: present knowledge and remaining challenges

ML Petroni, L Brodosi, F Marchignoli, AS Sasdelli… - Nutrients, 2021 - mdpi.com
Unhealthy behaviours, including diet and physical activity, coupled with genetic
predisposition, drive type 2 diabetes (T2D) occurrence and severity; the present review aims …

The role of zinc and copper in insulin resistance and diabetes mellitus

G Bjørklund, M Dadar, L Pivina… - Current medicinal …, 2020 - ingentaconnect.com
The prevalence of Type 2 Diabetes Mellitus (T2DM) is internationally ever-growing.
Therefore, prevention, diagnostics, and control of insulin resistance and T2DM are of …

Insights into pancreatic islet cell dysfunction from type 2 diabetes mellitus genetics

NAJ Krentz, AL Gloyn - Nature Reviews Endocrinology, 2020 - nature.com
Type 2 diabetes mellitus (T2DM) is an increasingly prevalent multifactorial disease that has
both genetic and environmental risk factors, resulting in impaired glucose homeostasis …

[HTML][HTML] Association between microbiota-dependent metabolite trimethylamine-N-oxide and type 2 diabetes

Z Shan, T Sun, H Huang, S Chen, L Chen, C Luo… - The American journal of …, 2017 - Elsevier
Background The association of trimethylamine-N-oxide (TMAO), a microbiota-dependent
metabolite from dietary choline and carnitine, with type 2 diabetes was inconsistent …

Solute carrier transporters as potential targets for the treatment of metabolic disease

T Schumann, J König, C Henke, DM Willmes… - Pharmacological …, 2020 - ASPET
The solute carrier (SLC) superfamily comprises more than 400 transport proteins mediating
the influx and efflux of substances such as ions, nucleotides, and sugars across biological …

[HTML][HTML] The play of genes and non-genetic factors on type 2 diabetes

M Mambiya, M Shang, Y Wang, Q Li, S Liu… - Frontiers in public …, 2019 - frontiersin.org
Diabetes has been a disease of public health concern for a number of decades. It was in the
1930s when scientists made an interesting discovery that the disease is actually divided into …

[HTML][HTML] Association of urinary metal profiles with altered glucose levels and diabetes risk: a population-based study in China

W Feng, X Cui, B Liu, C Liu, Y Xiao, W Lu, H Guo… - PloS one, 2015 - journals.plos.org
Background Elevated heavy metals and fasting plasma glucose (FPG) levels were both
associated with increased risk of cardiovascular diseases. However, studies on the …