Biomarkers of oxidative stress in metabolic syndrome and associated diseases

R Vona, L Gambardella, C Cittadini… - Oxidative medicine …, 2019 - Wiley Online Library
Metabolic syndrome (MS) represents worldwide public health issue characterized by a set of
cardiovascular risk factors including obesity, diabetes, dyslipidemia, hypertension, and …

The FoxO–autophagy axis in health and disease

Z Cheng - Trends in Endocrinology & Metabolism, 2019 - cell.com
Autophagy controls cellular remodeling and quality control. Dysregulated autophagy has
been implicated in several human diseases including obesity, diabetes, cardiovascular …

Changes in body weight, physical activity, and lifestyle during the semi-lockdown period after the outbreak of COVID-19 in China: an online survey

M He, Y Xian, X Lv, J He, Y Ren - Disaster medicine and public …, 2021 - cambridge.org
Objectives: The outbreak of novel coronavirus (COVID-19) provided an opportunity to
undertake an online survey to study the relationships between body weight changes with …

Early life nutrition, epigenetics and programming of later life disease

MH Vickers - Nutrients, 2014 - mdpi.com
The global pandemic of obesity and type 2 diabetes is often causally linked to marked
changes in diet and lifestyle; namely marked increases in dietary intakes of high energy …

Structure, function, and regulation of mitofusin‐2 in health and disease

G Chandhok, M Lazarou, B Neumann - Biological Reviews, 2018 - Wiley Online Library
Mitochondria are highly dynamic organelles that constantly migrate, fuse, and divide to
regulate their shape, size, number, and bioenergetic function. Mitofusins (Mfn1/2), optic …

Role of oxidative stress and inflammation in gestational diabetes mellitus

R Saucedo, C Ortega-Camarillo, A Ferreira-Hermosillo… - Antioxidants, 2023 - mdpi.com
Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications. It
is related to several gestational and fetal adverse outcomes. Moreover, women with GDM …

The role of mitochondria in myocardial damage caused by energy metabolism disorders: From mechanisms to therapeutics

A Li, L Lian, X Chen, W Cai, X Fan, Y Fan, T Li… - Free Radical Biology …, 2023 - Elsevier
Myocardial damage is the most serious pathological consequence of cardiovascular
diseases and an important reason for their high mortality. In recent years, because of the …

G protein-coupled bile acid receptor TGR5 activation inhibits kidney disease in obesity and diabetes

XX Wang, MH Edelstein, U Gafter, L Qiu… - Journal of the …, 2016 - journals.lww.com
Obesity and diabetes mellitus are the leading causes of renal disease. In this study, we
determined the regulation and role of the G protein-coupled bile acid receptor TGR5 …

Biological and clinical relevance of microRNAs in mitochondrial diseases/dysfunctions

D Sekar, J Johnson, M Biruntha, G Lakhmanan… - DNA and cell …, 2020 - liebertpub.com
Mitochondrial dysfunction arises from an inadequate number of mitochondria, an inability to
provide necessary substrates to mitochondria, or a dysfunction in their electron transport and …

Enhanced ROS production and oxidative damage in subcutaneous white adipose tissue mitochondria in obese and type 2 diabetes subjects

M Chattopadhyay, VK Khemka, G Chatterjee… - Molecular and cellular …, 2015 - Springer
Oxidative stress in the insulin target tissues has been implicated in the pathophysiology of
type 2 diabetes. The study has examined the oxidative stress parameters in the …