Recently, numerous studies have been conducted on Missing Value Imputation (MVI),
intending the primary solution scheme for the datasets containing one or more missing …

Richter syndrome (RS) is the transformation of chronic lymphocytic leukemia (CLL) into
aggressive lymphoma, most commonly diffuse large B-cell lymphoma (DLBCL). We …

In the dynamic landscape of targeted therapeutics, drug discovery has pivoted towards
understanding underlying disease mechanisms, placing a strong emphasis on molecular …

A key hallmark in the age‐related dysfunction of physiological systems is disruption related
to the regulation of inflammation, often resulting in a chronic, low‐grade inflammatory state …

Methylage is an epigenetic marker of biological age that exploits the correlation between the
methylation state of specific CG dinucleotides (CpGs) and chronological age (in years) …

Introduction: DNA methylation clocks presents advantageous characteristics with respect to
the ambitious goal of identifying very early markers of disease, based on the concept that …

Objective Obesity is associated with epigenetic age acceleration (EAA), resulting in an
increased risk of many age‐related disorders. However, most studies have focused on the …

Background DNA methylation has a significant effect on gene expression and can be
associated with various diseases. Meta-analysis of available DNA methylation datasets …

In recent years there has been a widespread interest in researching biomarkers of aging that
could predict physiological vulnerability better than chronological age. Aging, in fact, is one …

To highlight the genetic architecture for epigenetic aging, McCartney et al. recently identified
137 significant single-nucleotide polymorphisms based on genome-wide association study …