Epigenetics in rheumatoid arthritis
Epigenetics in rheumatoid arthritis : Current Opinion in Rheumatology Epigenetics in rheumatoid
arthritis : Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get …
arthritis : Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get …
Epigenetic regulation of chronic pain
Chronic pain arising from peripheral inflammation and tissue or nerve injury is a common
clinical symptom. Although intensive research on the neurobiological mechanisms of …
clinical symptom. Although intensive research on the neurobiological mechanisms of …
The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts
K Klein, PA Kabala, AM Grabiec, RE Gay… - Annals of the …, 2016 - ard.bmj.com
Objective To investigate the effects of BET bromodomain protein inhibition on inflammatory
activation and functional properties of rheumatoid arthritis synovial fibroblasts (RASF) …
activation and functional properties of rheumatoid arthritis synovial fibroblasts (RASF) …
Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis
G Benedetti, P Miossec - European journal of immunology, 2014 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory disease leading to joint destruction and
bone resorption. The proinflammatory cytokine interleukin 17 (IL‐17), primarily produced by …
bone resorption. The proinflammatory cytokine interleukin 17 (IL‐17), primarily produced by …
Rheumatoid arthritis–associated DNA methylation sites in peripheral blood mononuclear cells
H Zhu, LF Wu, XB Mo, X Lu, H Tang, XW Zhu… - Annals of the …, 2019 - ard.bmj.com
Objectives To identify novel DNA methylation sites significant for rheumatoid arthritis (RA)
and comprehensively understand their underlying pathological mechanism. Methods We …
and comprehensively understand their underlying pathological mechanism. Methods We …
The role of the synovial fibroblast in rheumatoid arthritis pathogenesis
The role of the synovial fibroblast in rheumatoid arthritis... : Current Opinion in
Rheumatology The role of the synovial fibroblast in rheumatoid arthritis pathogenesis …
Rheumatology The role of the synovial fibroblast in rheumatoid arthritis pathogenesis …
Estrogen, estrogen-like molecules and autoimmune diseases
J Merrheim, J Villegas, J Van Wassenhove… - Autoimmunity …, 2020 - Elsevier
In western countries, the slope of autoimmune disease (AD) incidence is increasing and
affects 5–8% of the population. Mainly prevalent in women, these pathologies are due to …
affects 5–8% of the population. Mainly prevalent in women, these pathologies are due to …
Epigenetic control of autoimmune diseases: from bench to bedside
A Picascia, V Grimaldi, O Pignalosa, MR De Pascale… - Clinical …, 2015 - Elsevier
Genome-wide association studies have revealed several genes predisposing to
autoimmunity, however, concordance rates in monozygotic twins are significantly below …
autoimmunity, however, concordance rates in monozygotic twins are significantly below …
Epigenetic alterations underlying autoimmune diseases
Recent breakthroughs in genetic explorations have extended our understanding through
discovery of genetic patterns subjected to autoimmune diseases (AID). Genetics, on the …
discovery of genetic patterns subjected to autoimmune diseases (AID). Genetics, on the …
Epigenetic alterations in chronic disease focusing on Behçet's disease
Objective 'Epigenetics' is specified as the inheritable changes in gene expression with no
alterations in DNA sequences. Epigenetics is a rapidly overspreading scientific field, and the …
alterations in DNA sequences. Epigenetics is a rapidly overspreading scientific field, and the …