C–H activation
T Rogge, N Kaplaneris, N Chatani, J Kim… - Nature Reviews …, 2021 - nature.com
Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform
for molecular syntheses, enabling applications to natural product syntheses, late-stage …
for molecular syntheses, enabling applications to natural product syntheses, late-stage …
Organic synthesis with the most abundant transition metal–iron: from rust to multitasking catalysts
In industries and academic laboratories, several late transition metal-catalyzed prerequisite
reactions are widely performed during single and multistep synthesis. However, besides the …
reactions are widely performed during single and multistep synthesis. However, besides the …
3d transition metals for C–H activation
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …
notable applications to material sciences, crop protection, drug discovery, and …
Advancing the logic of chemical synthesis: C− H activation as strategic and tactical disconnections for C− C bond construction
The design of synthetic routes by retrosynthetic logic is decisively influenced by the
transformations available. Transition‐metal‐catalyzed C− H activation has emerged as a …
transformations available. Transition‐metal‐catalyzed C− H activation has emerged as a …
[HTML][HTML] A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry
C Sambiagio, D Schönbauer, R Blieck… - Chemical Society …, 2018 - pubs.rsc.org
The present review is devoted to summarizing the recent advances (2015–2017) in the field
of metal-catalysed group-directed C–H functionalisation. In order to clearly showcase the …
of metal-catalysed group-directed C–H functionalisation. In order to clearly showcase the …
Construction of Quaternary Stereocenters by Palladium‐Catalyzed Carbopalladation‐Initiated Cascade Reactions
Y Ping, Y Li, J Zhu, W Kong - … Chemie International Edition, 2019 - Wiley Online Library
The enantioselective synthesis of molecules containing quaternary stereocenters is a field of
intense research interest and development. Among the known organic transformations …
intense research interest and development. Among the known organic transformations …
[HTML][HTML] The crucial role of silver (i)-salts as additives in C–H activation reactions: overall analysis of their versatility and applicability
RL de Carvalho, EBT Diogo, SL Homölle… - Chemical Society …, 2023 - pubs.rsc.org
Transition-metal catalyzed C–H activation reactions have been proven to be useful
methodologies for the assembly of synthetically meaningful molecules. This approach bears …
methodologies for the assembly of synthetically meaningful molecules. This approach bears …
Late‐stage peptide diversification by position‐selective C− H activation
The late‐stage modification of structurally complex peptides bears great potential for drug
discovery, crop protection, and the pharmaceutical industry, among others. Whereas …
discovery, crop protection, and the pharmaceutical industry, among others. Whereas …
Recent advances in transition metal-catalyzed heteroannulative difunctionalization of alkenes via C–H activation for the synthesis of heterocycles
J Liu, X Xiao, Y Lai, Z Zhang - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
Heterocyclic compounds are the fundamental structural motifs distributed in natural
products, pharmaceuticals and biologically active compounds. Thus, there is increasing …
products, pharmaceuticals and biologically active compounds. Thus, there is increasing …
[HTML][HTML] sp 3 C–H activation via exo-type directing groups
The application of exo-type directing groups (DGs) has led to the discovery of a wide range
of novel C (sp3)–H activation methods, which allow efficient and site-selective …
of novel C (sp3)–H activation methods, which allow efficient and site-selective …