[HTML][HTML] Markers of Futile Resuscitation in Traumatic Hemorrhage: A Review of the Evidence and a Proposal for Futility Time-Outs during Massive Transfusion

MM Walsh, MD Fox, EE Moore, JL Johnson… - Journal of Clinical …, 2024 - mdpi.com
The reduction in the blood supply following the 2019 coronavirus pandemic has been
exacerbated by the increased use of balanced resuscitation with blood components …

[HTML][HTML] Diagnostic value of sIL-2R, TNF-α and PCT for sepsis infection in patients with closed abdominal injury complicated with severe multiple abdominal injuries

G Zhai, W Zhang, Z Xiang, LZ He, W Wang… - Frontiers in …, 2021 - frontiersin.org
Objective We aimed to evaluate the diagnostic value of soluble interleukin-2 receptor (sIL-
2R), tumor necrosis factor-α (TNF-α), procalcitonin (PCT), and combined detection for sepsis …

Multicompartmental trauma induces persistent inflammation and organ injury

JA Munley, LS Kelly, GS Gillies, EE Pons… - Journal of Surgical …, 2024 - Elsevier
Introduction Previous preclinical models of multicompartmental injury have investigated its
effects for durations of less than 72 h and the long-term effects have not been defined. We …

[HTML][HTML] Lung failure after polytrauma with concomitant thoracic trauma in the elderly: an analysis from the TraumaRegister DGU®

JT Vollrath, CR Schindler, I Marzi, R Lefering… - World journal of …, 2022 - Springer
Background In developed countries worldwide, the number of older patients is increasing.
Pulmonary complications are common in multiple injured patients with chest injuries. We …

Unplanned readmissions following ambulatory spine surgery: assessing common reasons and risk factors

TB Amen, J Song, E Mai, SS Rudisill, P Bovonratwet… - The Spine Journal, 2023 - Elsevier
BACKGROUND CONTEXT Although outpatient spine surgery is becoming increasingly
popular in the United States, unplanned readmission following outpatient surgery remains a …

Transfusion futility thresholds and mortality in geriatric trauma: Does frailty matter?

JC L'Huillier, S Hua, HJ Logghe, J Yu… - The American Journal of …, 2024 - Elsevier
Background Data on massive transfusion (MT) in geriatric trauma patients is lacking. This
study aims to determine geriatric transfusion futility thresholds (TT) and TT variations based …

The Magic Number 63-Redefining the Geriatric Age for Massive Transfusion in Trauma

JC L'Huillier, HJ Logghe, S Hua, AA Myneni… - Journal of Surgical …, 2024 - Elsevier
Introduction The arbitrary geriatric age cutoff of 65 may not accurately define older adults at
higher risk of mortality following massive transfusion (MT). We sought to redefine a new …

A rat model of multicompartmental traumatic injury and hemorrhagic shock induces bone marrow dysfunction and profound anemia

LS Kelly, JA Munley, EE Pons… - Animal Models and …, 2024 - Wiley Online Library
Background Severe trauma is associated with systemic inflammation and organ dysfunction.
Preclinical rodent trauma models are the mainstay of postinjury research but have been …

[HTML][HTML] Effect of Emergency Scenario-Based Training Program on Knowledge, Self-confidence, and Competency of Elderly Caregiver Volunteers in a Rural Thai …

P Pongtriang, T Soontorn, J Sumleepun… - … Based Nursing and …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Many older people with comorbidities encounter emergency or life-threatening
situations, but the response is often neglected or delayed, resulting in increased morbidity …

Decline in explanatory power of trauma mortality models with age: varying contribution of Glasgow Coma Scale, Injury Severity Score, comorbidities, and frailty

Y Shen, A Orlando, SM Fakhry - Journal of surgical research, 2024 - Elsevier
Introduction Adjusting for confounding variables is critical for objective comparison of
outcomes. The explanatory power of variables used in adjusted models for injury and their …