Mitochondria lead the way: mitochondrial dynamics and function in cellular movements in development and disease

S Madan, B Uttekar, S Chowdhary… - Frontiers in Cell and …, 2022 - frontiersin.org
The dynamics, distribution and activity of subcellular organelles are integral to regulating
cell shape changes during various physiological processes such as epithelial cell formation …

A scarless healing tale: comparing homeostasis and wound healing of oral mucosa with skin and oesophagus

D Pereira, I Sequeira - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Epithelial tissues are the most rapidly dividing tissues in the body, holding a natural ability
for renewal and regeneration. This ability is crucial for survival as epithelia are essential to …

Diverse roles of TRPV4 in macrophages: A need for unbiased profiling

TN Nguyen, G Siddiqui, NA Veldhuis… - Frontiers in …, 2022 - frontiersin.org
Transient receptor potential vanilloid 4 (TRPV4) is a non-selective mechanosensitive ion
channel expressed by various macrophage populations. Recent reports have characterized …

Pan-cancer analysis of the TRP family, especially TRPV4 and TRPC4, and its expression correlated with prognosis, tumor microenvironment, and treatment sensitivity

Z Chen, Y Zhao, Y Tian, R Cao, D Shang - Biomolecules, 2023 - mdpi.com
Background: Transient receptor potential (TRP) channels are involved in various
physiological, pathological, and tumorigenesis-related processes. However, only a few …

Activation of transient receptor potential vanilloid 4 is involved in pressure overload-induced cardiac hypertrophy

Y Zou, M Zhang, Q Wu, N Zhao, M Chen, C Yang, Y Du… - Elife, 2022 - elifesciences.org
Previous studies, including our own, have demonstrated that transient receptor potential
vanilloid 4 (TRPV4) is expressed in hearts and implicated in cardiac remodeling and …

Calcium channels: noteworthy regulators and therapeutic targets in dermatological diseases

M Wang, Y Sun, L Li, P Wu, O Dkw, H Shi - Frontiers in pharmacology, 2021 - frontiersin.org
Dysfunctional skin barrier and impaired skin homeostasis may lead to or aggravate a series
of dermatologic diseases. A large variety of biological events and bioactive molecules are …

TRPV4 Regulates the Development of Psoriasis by Controlling Adenosine Triphosphate Expression in Keratinocytes and the Neuroimmune System

SN Amalia, H Baral, C Fujiwara, A Uchiyama… - Journal of Investigative …, 2023 - Elsevier
TRPV4 is a calcium ion channel that is widely expressed in various cells. It is also involved
in physiological and pathological processes. However, the role of TRPV4 in psoriasis …

Physiological and pathological significance of esophageal TRP channels: special focus on TRPV4 in esophageal epithelial cells

A Boudaka, M Tominaga - International Journal of Molecular Sciences, 2022 - mdpi.com
Transient receptor potential vanilloid 4 (TRPV4) is a non-selective cation channel that is
broadly expressed in different human tissues, including the digestive system, where it acts …

Wound Repair and Ca2+ Signalling Interplay: The Role of Ca2+ Channels in Skin

G Bonsignore, S Martinotti, E Ranzato - Cells, 2024 - mdpi.com
The process of wound healing is intricate and tightly controlled, involving a number of
different cellular and molecular processes. Numerous cellular functions, especially those …

[HTML][HTML] Interaction between TRP channels and anoctamins

Y Takayama, M Tominaga - Cell Calcium, 2024 - Elsevier
Abstract Anoctamin 1 (ANO1) binds to transient receptor potential (TRP) channels (protein-
protein interaction) and then is activated by TRP channels (functional interaction). TRP …