Benzodiazepines have been in use for over half a century. While they remain highly
prescribed, their unfavorable side-effect profile and abuse liability motivated a search for …

Abstract Alcohol Use Disorder (AUD) is a multifaceted relapsing disorder that is commonly
comorbid with psychiatric disorders, including anxiety. Alcohol exposure produces a …

Environmental factors, including substance abuse and stress, cause long-lasting changes in
the regulation of gene expression in the brain via epigenetic mechanisms, such as DNA …

Adolescent alcohol drinking is known to contribute to the development and severity of
alcohol use disorders (AUDs) later in adulthood. Recent studies have shown that long non …

Binge drinking during adolescence increases the risk for neuropsychiatric disorders
including alcoholism in adulthood. DNA methylation in post-mitotic neurons is an important …

GABAA receptors containing the α 6 subunit are highly expressed in cerebellar granule cells
and less abundantly in many other neuronal and peripheral tissues. Here, we for the first …

The high comorbidity of alcohol use disorder and depressive disorder is associated with
poor patient prognosis. The mechanisms underlying this comorbidity, however, are largely …

Prenatal ethanol exposure (PEE)(mainly through maternal alcohol consumption) has
become widespread. However, studies suggest that it can cause intrauterine growth …

Background Alcohol dependence is a mental disorder with a high relapse rate. However,
specific neuroimaging biomarkers have not been determined for alcohol dependence and …

Scope The aim of the current study is to evaluate whether l‐methionine supplementation (l‐
Met‐S) improves type 2 diabetes‐induced alterations in glucose and lipid metabolism by …