Mechanistic understanding of protein Corona formation around nanoparticles: old puzzles and new insights

K Nienhaus, GU Nienhaus - Small, 2023 - Wiley Online Library
Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …

COVID‐19 vaccine adverse events: Evaluating the pathophysiology with an emphasis on sulfur metabolism and endotheliopathy

HN du Preez, J Lin, GEM Maguire… - European Journal of …, 2024 - Wiley Online Library
In this narrative review, we assess the pathophysiology of severe adverse events that
presented after vaccination with DNA and mRNA vaccines against COVID‐19. The focus is …

Proteomic Analysis and Molecular Dynamics Simulation of Riboflavin-Coated Superparamagnetic Iron Oxide Nanoparticles Reveal Human Serum-Derived Protein …

W Mekseriwattana, W Phanchai… - ACS Applied Nano …, 2023 - ACS Publications
Superparamagnetic iron oxide nanoparticles (SPIONs) have been increasingly used as
nanomedicine platforms due to their exceptional magnetic properties, which emerged from …

Distinguishing Protein Corona from Nanoparticle Aggregate Formation in Complex Biological Media Using X-ray Photon Correlation Spectroscopy

CEP Silva, AS Picco, FE Galdino… - Nano Letters, 2024 - ACS Publications
In biological systems, nanoparticles interact with biomolecules, which may undergo protein
corona formation that can result in noncontrolled aggregation. Therefore, comprehending …

Enhanced stability of Pickering emulsions through co-stabilization with nanoliposomes and thermally denatured ovalbumin

J Gu, M Pan, Y Chiou, S Wei, B Ding - International Journal of Biological …, 2024 - Elsevier
Pickering emulsions were co-stabilized by nanoliposome (NL) and thermally denatured
ovalbumin (DOVA) based on the induction of OVA with strong particle characteristics …

Specific nanoarchitecture of silica nanoparticles codoped with the oppositely charged Mn2+ and Ru2+ complexes for dual paramagnetic-luminescent contrasting …

S Fedorenko, A Stepanov, O Bochkova, K Kholin… - … , Biology and Medicine, 2023 - Elsevier
The silica nanoparticles (SNs) co-doped with paramagnetic ([Mn (HL)] n-,) and luminescent
([Ru (dipy) 3] 2+) complexes are represented. The specific distribution of [Mn (HL)] n-within …

Hydrodynamics and Aggregation of Nanoparticles with Protein Corona: Effects of Protein Concentration and Ionic Strength

H Lee - Small, 2024 - Wiley Online Library
Multiple 10 nm‐sized anionic nanoparticles complexed with plasma proteins (human serum
albumin (SA) or immunoglobulin gamma‐1 (IgG)) at different ratios are simulated using all …

Competitive effects of salt and surfactant on the structure of nanoparticles in a binary system of nanoparticle and protein

D Saha, S Kumar, JP Mata, AE Whitten… - Physical Chemistry …, 2023 - pubs.rsc.org
Small-angle neutron scattering (SANS) and dynamic light scattering (DLS) experiments
have been carried out to study the competitive effects of NaCl and sodium dodecyl sulfate …

N, N, N-Trimethyl chitosan as a permeation enhancer for inhalation drug delivery: interaction with a model pulmonary surfactant

J Szabová, F Mravec, M Mokhtari, R Le Borgne… - International Journal of …, 2023 - Elsevier
Abstract N, N, N-Trimethyl chitosan (TMC), a biocompatible and biodegradable derivative of
chitosan, is currently used as a permeation enhancer to increase the translocation of drugs …

Selenium Nanoparticles Can Influence the Immune Response Due to Interactions with Antibodies and Modulation of the Physiological State of Granulocytes

VV Khabatova, DA Serov, IV Tikhonova, ME Astashev… - Pharmaceutics, 2022 - mdpi.com
Currently, selenium nanoparticles (SeNPs) are considered potential immunomodulatory
agents and as targets for activity modulation are granulocytes, which have the most …