[PDF][PDF] Role of pharmacokinetic studies in drug discovery
T Nishant, D Sathish Kumar, PM Arun Kumar - J Bioequiv Availab, 2011 - academia.edu
Over the last few years, Pharmacokinetics has emerged as an integral part of drug
development, especially when identifying a drug's biological properties. Understanding of …
development, especially when identifying a drug's biological properties. Understanding of …
[PDF][PDF] Analysis of pharmacokinetic & pharmacodynamic models in oral and transdermal dosage forms
D Parthasarathi, C Gajendra, A Dattatreya… - J Bioequiv …, 2011 - researchgate.net
Bioavailability is a pharmacokinetic term which refers the extent and speed of absorption of
the chemicals content in it. After the absorption the drug plays the important role in which the …
the chemicals content in it. After the absorption the drug plays the important role in which the …
富马酸喹硫平片人体生物等效性研究
戴婕， 李芳芳， 陈庆强， 谭焕君， 胡晋卿… - 中国现代应用 …, 2013 - zgxdyyyx.ijournals.cn
目的研究国产富马酸喹硫平片的生物等效性. 方法20 名健康男性志愿者按标准二阶段交叉试验
方案设计, 分别口服受试制剂和参比制剂各200 mg, 并采集36 h 内动态血标本, 用HPLC-MS/MS …
方案设计, 分别口服受试制剂和参比制剂各200 mg, 并采集36 h 内动态血标本, 用HPLC-MS/MS …
[PDF][PDF] Design, development and in vitro evaluation OF controlled release gel for topical delivery of quetiapine using box-behnken design
HK Patel, CV Shah, VH Shah, UM Upadhyay - International Journal of …, 2012 - Citeseer
The purpose of this work was to develop and characterize a vesicular drug carrier for topical
delivery of Quetiapine to overcome the problems related with oral route that is high first pass …
delivery of Quetiapine to overcome the problems related with oral route that is high first pass …
Selection of Healthy Volunteers According to their Multidrug Resistance Protein 1 Activity Does Not Affect Bioavailability of Quetiapine
LI Castro-Pastrana, O Guzman-Ruiz… - Current …, 2016 - ingentaconnect.com
Background: Quetiapine-an antipsychotic multidrug resistance protein 1 (MDR-1) substrate-
has a large interindividual variability in its pharmacokinetics. Objective: In order to unravel …
has a large interindividual variability in its pharmacokinetics. Objective: In order to unravel …
Steady-state pharmacokinetics and bioequivalence study of quetiapine fumarate film-coated tablets 300 mg in adult schizophrenic patients
MR Betha, SK Tippabhotla, S Yergude… - Clinical Research …, 2012 - Taylor & Francis
Quetiapine is a dibenzothiazepine derivative approved for the treatment of schizophrenia
and related psychoses. The objective of the present study was to design and evaluate the …
and related psychoses. The objective of the present study was to design and evaluate the …
[PDF][PDF] INTERNATIONAL RESEARCH JOURNAL OF PHARMACY
Analytical methods development and validation play significant roles in the drug discovery,
development, manufacture of pharmaceuticals and estimation of small molecules. The …
development, manufacture of pharmaceuticals and estimation of small molecules. The …
[引用][C] Factorial designing, development and in-vitro evaluation of liposomal gel for topical delivery of quetiapine
HK Patel, CV Shah, VH Shah, UM Upadhyay - Asian J. Pharm. Sci, 2012